Arachidin-1, a prenylated stilbenoid from peanut, enhances the anticancer effects of paclitaxel in triple-negative breast cancer cells

S Mohammadhosseinpour, A Weaver, M Sudhakaran… - Cancers, 2023 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is an aggressive type of cancer that
is challenging to treat due to the lack of hormonal receptors used to target cancer cells; due …

Arachidin-1, a prenylated stilbenoid from peanut, induces apoptosis in triple-negative breast cancer cells

S Mohammadhosseinpour, LC Ho, L Fang… - International Journal of …, 2022 - mdpi.com
Triple-negative breast cancer (TNBC) is unresponsive to typical hormonal treatments,
causing it to be one of the deadliest forms of breast cancer. Investigating alternative …

Garcinol sensitizes breast cancer cells to Taxol through the suppression of caspase-3/iPLA 2 and NF-κB/Twist1 signaling pathways in a mouse 4T1 breast tumor …

SH Tu, YS Chiou, N Kalyanam, CT Ho, LC Chen… - Food & function, 2017 - pubs.rsc.org
Breast cancer is a significant threat to women's health and has high incidence and mortality.
Metastasis in breast cancer patients is a major cause of cancer deaths among women …

Naringin inhibits growth potential of human triple-negative breast cancer cells by targeting β-catenin signaling pathway

H Li, B Yang, J Huang, T Xiang, X Yin, J Wan, F Luo… - Toxicology letters, 2013 - Elsevier
Triple-negative (ER-/PR-/HER2-) breast cancer (TNBC) is a severe clinical problem because
of its relatively poorer prognosis, aggressive behavior and lack of targeted therapies …

N-phenyl pyrazoline derivative inhibits cell aggressiveness and enhances paclitaxel sensitivity of triple negative breast cancer cells

PB Satriyo, M Mustofa, TD Wahyuningsih… - Scientific Reports, 2024 - nature.com
Protein kinase dysregulation induces cancer cell aggressiveness leading to rapid tumor
progression and poor prognosis in TNBC patients. Many small-molecule kinase inhibitors …

10-Gingerol enhances the effect of taxol in triple-negative breast cancer via targeting ADRB2 signaling

Y Liang, G Wu, T Luo, H Xie, Q Zuo… - Drug Design …, 2023 - Taylor & Francis
Purpose Although paclitaxel is widely used in cancer treatment, severe side effects and drug
resistance limit its clinical use. 10-gingerol (10-G) is a natural compound isolated from …

The Modulatory Properties of Astragalus membranaceus Treatment on Triple-Negative Breast Cancer: An Integrated Pharmacological Method

C Liu, K Wang, J Zhuang, C Gao, H Li, L Liu… - Frontiers in …, 2019 - frontiersin.org
Background: Studies have shown that the natural products of Astragalus membranaceus
(AM) can effectively interfere with a variety of cancers, but their mechanism of action on …

[HTML][HTML] Phytoagent deoxyelephantopin derivative inhibits triple negative breast cancer cell activity by inducing oxidative stress-mediated paraptosis-like cell death

JY Shiau, K Nakagawa-Goto, KH Lee, LF Shyur - Oncotarget, 2017 - ncbi.nlm.nih.gov
Triple negative breast cancer (TNBC) is a highly metastatic cancer among the breast cancer
subgroups. A thorny issue for clinical therapy of TNBC is lack of an efficient targeted …

[HTML][HTML] Arnicolide d inhibits triple negative breast cancer cell proliferation by suppression of Akt/mTOR and STAT3 signaling pathways

Z Qu, Y Lin, DKW Mok, Q Bian, WCS Tai… - International Journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Triple-Negative Breast Cancer (TNBC) is a most dangerous breast cancer subtype.
The naturally occurring sesquiterpene lactone, arnicolide D (AD), has proven effective …

Discovery of 8,9-seco-ent-Kaurane Diterpenoids as Potential Leads for the Treatment of Triple-Negative Breast Cancer

RZ Fan, L Chen, T Su, W Li, JL Huang… - Journal of Medicinal …, 2021 - ACS Publications
Triple-negative breast cancer (TNBC) is a lethal malignancy without safe and effective
therapeutic drugs. In this study, the anti-TNBC bioassay-guided isolation of the medicinal …