Macrohemodynamic targets such as mean arterial pressure, cardiac output, and mixed or
central venous oxygen saturation have been used to guide treatment of patients presenting …

What is microcirculatory shock? : Current Opinion in Critical Care What is microcirculatory
shock? : Current Opinion in Critical Care Log in or Register Subscribe to journalSubscribe Get …

Shock is characterized by an alteration in tissue perfusion that may lead to tissue hypoxia.
Recent guidelines recommend aggressive and early resuscitation therapy, but mortality rate …

Objectives: A dysfunctional microcirculation is universal in shock and is often dissociated
from global hemodynamic parameters. Persistent microcirculatory derangements reflect …

In severe sepsis and septic shock the severe impairment of the microcirculation is one of the
main reasons for tissue hypoxia, multiple organ failure and death. Fast resuscitation of the …

Microcirculatory alterations, frequently observed in shock states, are associated with the
development of multiple organ failure and death. These microcirculatory alterations occur …

Microcirculatory perfusion is disturbed in sepsis. Recent research has shown that
maintaining systemic blood pressure is associated with inadequate perfusion of the …

Shock, defined at a cellular level, is a condition in which oxygen delivery to the cells is not
sufficient to sustain cellular activity and support organ function. The central role of …

Septic shock is a life-threatening condition in both critically ill medical patients and surgical
patients during the perioperative phase. In septic shock, specific alterations in global …

Early goal-directed therapy with maintenance of adequate central venous pressure (CVP),
mean arterial pressure (MAP), and central venous oxygen saturation (ScvO 2) fails to …