[HTML][HTML] The 5-HT1B receptor - a potential target for antidepressant treatment
M Tiger, K Varnäs, Y Okubo, J Lundberg - Psychopharmacology, 2018 - Springer
Major depressive disorder (MDD) is the leading cause of disability worldwide. The serotonin
hypothesis may be the model of MDD pathophysiology with the most support. The majority of …
hypothesis may be the model of MDD pathophysiology with the most support. The majority of …
The 5-HT1A receptor in major depressive disorder
J Kaufman, C DeLorenzo, S Choudhury… - European …, 2016 - Elsevier
Abstract Major Depressive Disorder (MDD) is a highly prevalent psychiatric diagnosis that is
associated with a high degree of morbidity and mortality. This debilitating disorder is …
associated with a high degree of morbidity and mortality. This debilitating disorder is …
5-HT2A antagonists in psychiatric disorders.
L de Angelis - Current Opinion in Investigational drugs (London …, 2002 - europepmc.org
Several lines of evidence support a role for serotoninergic (5-HT) system abnormalities in
the pathogenesis and treatment of several psychiatric disorders. This review summarizes …
the pathogenesis and treatment of several psychiatric disorders. This review summarizes …
Interplay between Serotonin 5‐HT1A and 5‐HT7 Receptors in Depressive Disorders
VS Naumenko, NK Popova, E Lacivita… - CNS neuroscience & …, 2014 - Wiley Online Library
Summary Serotonin (5‐hydroxytryptamine or 5‐HT) is an important neurotransmitter
regulating a wide range of physiological and pathological functions via activation of …
regulating a wide range of physiological and pathological functions via activation of …
5-HT2C receptors in psychiatric disorders: a review
HT2Rs have a different genomic organization from other 5-HT2Rs. 5HT2CR undergoes post-
transcriptional pre-mRNA editing generating diversity among RNA transcripts. Selective post …
transcriptional pre-mRNA editing generating diversity among RNA transcripts. Selective post …
[HTML][HTML] Role of 5-HT3 Receptors in the Antidepressant Response
Serotonin (5-HT) 3 receptors are the only ligand-gated ion channel of the 5-HT receptors
family. They are present both in the peripheral and central nervous system and are localized …
family. They are present both in the peripheral and central nervous system and are localized …
The 5-HT1B receptor: behavioral implications.
MS Clark, JF Neumaier - Psychopharmacology bulletin, 2001 - europepmc.org
5-HT1B receptors are expressed throughout the mammalian central nervous system. These
receptors are located in the axon terminals of both serotonergic and nonserotonergic …
receptors are located in the axon terminals of both serotonergic and nonserotonergic …
The 5-HT2C receptor as a target for mood disorders
A Serretti, P Artioli, D De Ronchi - Expert opinion on therapeutic …, 2004 - Taylor & Francis
The serotonin (5-hydroxytryptamine2C [5-HT2C]) receptor is one of the 5-HT receptors with
a G-protein-coupled intracellular signalling pathway. A large number of compounds showing …
a G-protein-coupled intracellular signalling pathway. A large number of compounds showing …
New therapeutic opportunities for 5-HT2C receptor ligands in neuropsychiatric disorders
G Di Giovanni, P De Deurwaerdère - Pharmacology & therapeutics, 2016 - Elsevier
Abstract The 5-HT 2C receptor (R) displays a widespread distribution in the CNS and is
involved in the action of 5-HT in all brain areas. Knowledge of its functional role in the CNS …
involved in the action of 5-HT in all brain areas. Knowledge of its functional role in the CNS …
Behavioural pharmacology of 5-HT3 receptor ligands
JM Barnes, NM Barnes, SJ Cooper - Neuroscience & Biobehavioral …, 1992 - Elsevier
Extensive studies have ascribed a role for the central 5-HT 3 receptor in the modulation of
behaviour. Much of the work stems from the actions of potent and selective 5-HT 3 receptor …
behaviour. Much of the work stems from the actions of potent and selective 5-HT 3 receptor …