The mammalian genome contains both constitutively expressed and heat‐shock‐inducible
members of the hsp70 gene family. Riboprobes derived from members of these two classes …

We have previously reported that hyperthermia induces the expression of a heat shock gene
in the rabbit brain (Sprang and Brown, Mol Brain Res 3: 89–93, 1987). Striking regional and …

Northern blot and in situ hybridization were employed to investigate regional and cell type
differences in the expression of hsp90 mRNA species in control and hyperthermic rabbit …

Although the induction of heat shock proteins (HSP) has been studied extensively in
cultured cells, comparatively few studies have examined their expression in vivo. In this …

In previous studies we have analyzed the effect of hyperthermia on the expression of hsp 70
genes in the rabbit cerebellum using an hsp70 riboprobe which hybridized to both …

We have previously investigated the expression of hsp70 genes in the hyperthermic rabbit
brain at the mRNA level by Northern blot and in situ hybridization procedures. Our studies …

Cloned fragments of members of the Drosophila and mouse major heat shock (hsp70) gene
family were used to demonstrate that homologous sequences are present in the rabbit …

Studies on heat shock proteins have dealt with a wide range of organisms including E. coli,
Saccharomyces, Drosophila and vertebrate cells grown in culture (Schlesinger et al. 1982; …

The expression of mRNAs encoding two members of the heat‐shock protein 70 family, the
constitutively‐expressed heat‐shock cognate (hsc70) mRNA and the strictly heat‐inducible …

A number of studies have demonstrated increased synthesis of heat shock proteins in brain
following hyperthermia or transient ischemia. In the present experiments we have …