Myocardial ischemia-reperfusion injury; Molecular mechanisms and prevention

Y Liu, L Li, Z Wang, J Zhang, Z Zhou - Microvascular Research, 2023 - Elsevier
Cardiovascular diseases are one of the leading causes of mortality in developed countries.
Among cardiovascular disorders, myocardial infarction remains a life-threatening problem …

[HTML][HTML] An overview of the molecular mechanisms associated with myocardial ischemic injury: state of the art and translational perspectives

L Schirone, M Forte, L D'Ambrosio, V Valenti… - Cells, 2022 - mdpi.com
Cardiovascular disease is the leading cause of death in western countries. Among
cardiovascular diseases, myocardial infarction represents a life-threatening condition …

A review of myocardial ischaemia/reperfusion injury: pathophysiology, experimental models, biomarkers, genetics and pharmacological treatment

M Gunata, H Parlakpinar - Cell biochemistry and function, 2021 - Wiley Online Library
Cardiovascular diseases are known to be the most fatal diseases worldwide.
Ischaemia/reperfusion (I/R) injury is at the centre of the pathology of the most common …

[PDF][PDF] Pathophysiology of myocardial ischemia reperfusion injury: a review

H Parlakpinar, MH Orum, M Sagir - Medicine Science, 2013 - dergipark.org.tr
Cardiovascular events are one of the leading causes of death in the world. Thrombolysis,
percutaneous transluminal coronary angioplasty, and coronary bypass surgery are the …

[HTML][HTML] Myocardial ischemia/reperfusion injury: Mechanisms of injury and implications for management

J He, D Liu, L Zhao, D Zhou… - Experimental and …, 2022 - spandidos-publications.com
Myocardial infarction is one of the primary causes of mortality in patients with coronary heart
disease worldwide. Early treatment of acute myocardial infarction restores blood supply of …

[HTML][HTML] The role and mechanisms of microvascular damage in the ischemic myocardium

BH Zhao, A Ruze, L Zhao, QL Li, J Tang… - Cellular and Molecular …, 2023 - Springer
Following myocardial ischemic injury, the most effective clinical intervention is timely
restoration of blood perfusion to ischemic but viable myocardium to reduce irreversible …

Ischemia-reperfusion-induced cardiac injury: a brief review.

SK Powers, Z Murlasits, M Wu… - Medicine and science in …, 2007 - europepmc.org
Myocardial ischemia-reperfusion (IR) injury is the primary contributor to the morbidity and
mortality associated with coronary artery disease. Depending on the duration of ischemia …

[HTML][HTML] Clinical manifestations and basic mechanisms of myocardial ischemia/reperfusion injury

CF Yang - Tzu Chi Medical Journal, 2018 - journals.lww.com
Acute myocardial ischemia/reperfusion (I/R) injury is a significant, unsolved clinical puzzle.
In the disease context of acute myocardial infarction, reperfusion remains the only effective …

Myocardial ischaemia–reperfusion injury and cardioprotection in perspective

G Heusch - Nature Reviews Cardiology, 2020 - nature.com
Despite the increasing use and success of interventional coronary reperfusion strategies,
morbidity and mortality from acute myocardial infarction are still substantial. Myocardial …

Myocardial ischemia reperfusion injury: from basic science to clinical bedside

A Frank, M Bonney, S Bonney… - Seminars in …, 2012 - journals.sagepub.com
Myocardial ischemia reperfusion injury contributes to adverse cardiovascular outcomes after
myocardial ischemia, cardiac surgery or circulatory arrest. Primarily, no blood flow to the …