Methionine sulfoxide reductase A (MsrA), an efflux pump belonging to ATP-binding cassette
(ABC) transporter family that conferred resistance to macrolides, was detected in …

The emergence of multiple drug resistant pathogenic bacteria has severely constricted the
antimicrobial options of treating infectious diseases. One of the powerful mechanisms of …

In this study, hemolysis, Western blot, and real-time RT-PCR assays were performed to
evaluate silibininʼs activity against S. aureus α-toxin secretion. In addition, live/dead cell …

Wounds provide a favourable site for microbial infection. Wound infection makes the healing
more complex and does not proceed in an orchestrated manner leading to the chronic …

Plants contain many bioactive compounds with potent antibacterial and efflux pump
inhibitory activity (EPI). In this study, gallic acid extracted from pomegranate molasses by …

Multidrug-resistant pathogens are a significant clinical problem. Efflux pump inhibitors (EPIs)
can restore the activities of existing antibiotics by interfering with drug efflux pumps located …

Antibiotic resistant bacteria (ABR) is an alarming issue and it has to be eliminated before
enter into the environment. The role of efflux pump inhibitor, reserpine–a plant alkaloid in …

Compounds capable of inhibiting the efflux pump mechanism are a promising alternative
against bacterial resistance because, when combined with antibiotics, they can increase the …

Silibinin have been introduced for several years as a potent antioxidant in the field of
nutraceuticals. Based on wide persuasive effects of this drug, we have decided to …