The development of multiple drug resistance organisms (MDR) is a major threat, and due to
this emergence, it is found that it is difficult to treat many infectious diseases. Synergistic …

The surge in multidrug resistance (MDR) in the bacterial system has constricted the use of
foregoing therapeutics for the treatment of fatal infections. The primary factor responsible for …

Background: In recent years, drug resistance to human pathogenic bacteria has been
commonly reported from all over the world. As antimicrobial activities of most medicinal …

Efflux pumps are integral parts of the bacterial plasma membrane that are responsible for
many cases of antibiotic resistance. Modulators of drug resistance are regarded as the most …

Abstract Ethnopharmacological relevance Zingiber officinale Roscoe has been utilized
traditionally to cure various diseases like cold, cough, diarrhoea, nausea, asthma, vomiting …

Antimicrobial resistance among microorganisms is an alarming and increasing problem
throughout the world [1-3]. The widespread use of antibiotics led to the development of multi …

Piperine, a major plant alkaloid found in black pepper (Piper nigrum) and long pepper (Piper
longum), has shown potential for inhibiting the efflux pump (EP) of Staphylococcus aureus …

Antibiotic resistance or microbial drug resistance is emerging as a serious threat to human
healthcare globally, and the multidrug-resistant (MDR) strains are imposing major hurdles to …

The in-house IIIM natural product repository of 302 small molecules was screened for their
ability to inhibit P-glycoprotein (Pgp) in Pgp-overexpressing human adenocarcinoma LS …

The rapid emergence of resistant bacteria is occurring worldwide, endangering the efficacy
of antibiotics, which have transformed medicine and saved millions of lives. Antibiotic …