1. We set out to define abnormalities of oxidative ATP synthesis, cellular proton efflux and
the efficiency of ATP usage in gastrocnemius muscle of patients with claudication due to …

Objective: Decreased oxygen supply is generally accepted as the primary cause of muscle
dysfunction in patients with peripheral arterial occlusive disease (PAOD) and intermittent …

This study tested the hypotheses that skeletal muscle mitochondrial ATP production rate
(MAPR) is impaired in patients with peripheral arterial disease (PAD) and that it relates …

Purpose: We used 31P magnetic resonance spectroscopy (MRS) and near-infrared
spectroscopy (NIRS) as a means of quantifying abnormalities in calf muscle oxygenation …

Energy metabolism of calf muscle was assessed non‐invasively by phosphorus (31P) NMR
spectroscopy in eleven patients with symptomatic arterial occlusion and in seven matched …

The behaviour of muscular metabolism was investigated in 10 patients with peripheral
arterial occlusive disease stage II at rest and after maximum erometric calf exercise. The …

In exercising muscle, creatine kinase ensures that mismatch between ATP supply and ATP
use results in net phosphocreatine (PCr) splitting. This, inter alia, makes 31 P magnetic …

We use the hyperbolic relationship between cytosolic [ADP] and the rate of phosphocreatine
(PCr) resynthesis after exercise to estimate the apparent maximum rate of oxidative ATP …

OBJECTIVE: To identify differences in postexercise phosphocreatine (PCr) recovery, an
index of mitochondrial function, in diabetic patients with and without lower extremity …

In peripheral vascular disease, impaired muscle energy metabolism is assumed to be due
mainly to defective vascular O2 supply, the resulting cellular hypoxia inhibiting oxidative …