Background Neuromyelitis optica spectrum disorders (NMOSD) are severe central nervous
system inflammatory demyelinating disorders (CNS IDD) characterized by monophasic or …

Background The presence of antibodies to aquaporin-4 (AQP4) has been identified as a key
characteristic of neuromyelitis optica spectrum disorder (NMOSD), an autoimmune …

Abstract Background In 70-80% of cases, neuromyelitis optica (NMO) is associated with
highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG) …

NMO‐I g G against aquaporin‐4 (AQP 4) is a specific marker for neuromyelitis optica (NMO).
We evaluated the performance of different NMO‐I g G detecting methods. In 124 sera (from …

Objective Antibodies to cell surface central nervous system proteins help to diagnose
conditions which often respond to immunotherapies. The assessment of antibody assays …

Neuromyelitis optica spectrum disorders (NMOSD) are associated with anti-aquaporin-4
autoantibodies (AQP4-IgG). Limited data is available on longitudinal cerebrospinal fluid …

Background Although rare, brain abnormalities without optic neuritis (ON) or transverse
myelitis (TM) diagnosed with neuromyelitis optica spectrum disorder (NMOSD) have been …

Objective To develop a cell-based assay (CBA) to detect aquaporin 1 (AQP1) antibodies
and determine sensitivity/specificity in patients with neuromyelitis optica (NMO) spectrum …

Importance: The term neuromyelitis optica spectrum disorders (NMOSD) currently includes
neuromyelitis optica (NMO) and rare neurological disorders characterized by specific IgG …

Although more than 70% of all patients with neuromyelitis optica (NMO) are seropositive for
aquaporin-4 (AQP4) antibodies, a substantial proportion of patients fulfilling the clinical …