Predicting potential cancer genes by integrating network properties, sequence features and functional annotations
W Liu, HW Xie - Science China Life Sciences, 2013 - Springer
The discovery of novel cancer genes is one of the main goals in cancer research.
Bioinformatics methods can be used to accelerate cancer gene discovery, which may help in …
Bioinformatics methods can be used to accelerate cancer gene discovery, which may help in …
[HTML][HTML] Essentiality, protein–protein interactions and evolutionary properties are key predictors for identifying cancer-associated genes using machine learning
The distinctive nature of cancer as a disease prompts an exploration of the special
characteristics the genes implicated in cancer exhibit. The identification of cancer …
characteristics the genes implicated in cancer exhibit. The identification of cancer …
[HTML][HTML] Discovering cancer genes by integrating network and functional properties
L Li, K Zhang, J Lee, S Cordes, DP Davis… - BMC medical genomics, 2009 - Springer
Background Identification of novel cancer-causing genes is one of the main goals in cancer
research. The rapid accumulation of genome-wide protein-protein interaction (PPI) data in …
research. The rapid accumulation of genome-wide protein-protein interaction (PPI) data in …
[PDF][PDF] Prediction of core cancer genes using a hybrid of feature selection and machine learning methods
YX Liu, NN Zhang, Y He, LJ Lun - Genetics and Molecular …, 2015 - m.jstshuichan.com
Machine learning techniques are of great importance in the analysis of microarray
expression data, and provide a systematic and promising way to predict core cancer genes …
expression data, and provide a systematic and promising way to predict core cancer genes …
[HTML][HTML] Incorporating gene co-expression network in identification of cancer prognosis markers
Background Extensive biomedical studies have shown that clinical and environmental risk
factors may not have sufficient predictive power for cancer prognosis. The development of …
factors may not have sufficient predictive power for cancer prognosis. The development of …
Integrative gene network construction for predicting a set of complementary prostate cancer genes
Motivation: Diagnosis and prognosis of cancer and understanding oncogenesis within the
context of biological pathways is one of the most important research areas in bioinformatics …
context of biological pathways is one of the most important research areas in bioinformatics …
Identification of genes of four malignant tumors and a novel prediction model development based on PPI data and support vector machines
M Li, P Wang, N Zhang, L Guo, YM Feng - Cancer gene therapy, 2020 - nature.com
Triple-negative breast cancer (TNBC), colon adenocarcinoma (COAD), ovarian cancer (OV),
and glioblastoma multiforme (GBM) are common malignant tumors, in which significant …
and glioblastoma multiforme (GBM) are common malignant tumors, in which significant …
Machine learning-based approaches for disease gene prediction
DH Le - Briefings in functional genomics, 2020 - academic.oup.com
Disease gene prediction is an essential issue in biomedical research. In the early days,
annotation-based approaches were proposed for this problem. With the development of high …
annotation-based approaches were proposed for this problem. With the development of high …
[HTML][HTML] Contextualizing genes by using text-mined co-occurrence features for cancer gene panel discovery
HO Chen, PC Lin, CR Liu, CS Wang… - Frontiers in Genetics, 2021 - frontiersin.org
Developing a biomedical-explainable and validatable text mining pipeline can help in
cancer gene panel discovery. We create a pipeline that can contextualize genes by using …
cancer gene panel discovery. We create a pipeline that can contextualize genes by using …
Enhancing cancer driver gene prediction by protein-protein interaction network
With the advances in gene sequencing technologies, millions of somatic mutations have
been reported in the past decades, but mining cancer driver genes with oncogenic …
been reported in the past decades, but mining cancer driver genes with oncogenic …