Comparison of ticagrelor vs clopidogrel in addition to aspirin in patients with minor ischemic stroke and transient ischemic attack: a network meta-analysis

R Lun, S Dhaliwal, G Zitikyte, DC Roy, B Hutton… - JAMA …, 2022 - jamanetwork.com
Importance Dual antiplatelet therapy (DAPT) with clopidogrel and aspirin is effective in
preventing recurrent strokes after minor ischemic stroke or transient ischemic attack (TIA) …

Efficacy and safety of ticagrelor and aspirin in patients with moderate ischemic stroke: an exploratory analysis of the THALES randomized clinical trial

Y Wang, Y Pan, H Li, P Amarenco, H Denison… - JAMA …, 2021 - jamanetwork.com
Importance Prior trials of dual antiplatelet therapy excluded patients with moderate ischemic
stroke. These patients were included in the Acute Stroke or Transient Ischaemic Attack …

Antiplatelet therapy for transient ischemic attack and minor stroke

Y Xiong, PM Bath - Stroke, 2020 - Am Heart Assoc
Transient ischemic attack (TIA) and minor stroke account for 30% to 50% of all cerebral
ischemic events around the world. 1, 2 In the acute setting, mono-antiplatelet therapy …

Ticagrelor added to aspirin in acute nonsevere ischemic stroke or transient ischemic attack of atherosclerotic origin

P Amarenco, H Denison, SR Evans, A Himmelmann… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: Among patients with a transient ischemic attack or minor ischemic
strokes, those with ipsilateral atherosclerotic stenosis of cervicocranial vasculature have the …

Ticagrelor added to aspirin in acute ischemic stroke or transient ischemic attack in prevention of disabling stroke: a randomized clinical trial

P Amarenco, H Denison, SR Evans… - JAMA …, 2021 - jamanetwork.com
Importance Reduction of subsequent disabling stroke is the main goal of preventive
treatment in the acute setting after transient ischemic attack (TIA) or minor ischemic stroke …

Effect of hypertension on efficacy and safety of ticagrelor-aspirin versus clopidogrel-aspirin in minor stroke or transient ischemic attack

A Wang, X Meng, X Tian, SC Johnston, H Li, PM Bath… - Stroke, 2022 - Am Heart Assoc
Background: Hypertension is a risk factor of poor stroke outcomes and associated with
antiplatelet resistance. This study aimed to explore the efficacy and safety of ticagrelor …

Effect of ticagrelor with clopidogrel on high on-treatment platelet reactivity in acute stroke or transient ischemic attack (PRINCE) trial: rationale and design

Y Wang, Y Lin, X Meng, W Chen, G Chen, Z Wang… - 2017 - journals.sagepub.com
Rationale and aim Little is known about the safety and efficacy of the combination of
ticagrelor and aspirin in acute ischemic stroke. This study aimed to evaluate whether the …

Ticagrelor plus aspirin versus clopidogrel plus aspirin for platelet reactivity in patients with minor stroke or transient ischaemic attack: open label, blinded endpoint …

Y Wang, W Chen, Y Lin, X Meng, G Chen, Z Wang… - bmj, 2019 - bmj.com
Objective To test the hypothesis that ticagrelor plus aspirin is safe and superior to
clopidogrel plus aspirin for reducing high platelet reactivity at 90 days and stroke recurrence …

P2Y12 inhibitors plus aspirin versus aspirin alone in patients with minor stroke or high-risk transient ischemic attack

ZX Li, Y Xiong, HQ Gu, M Fisher, Y Xian, SC Johnston… - Stroke, 2021 - Am Heart Assoc
Background and purpose: We performed a systemic review and meta-analysis to elucidate
the effectiveness and safety of dual antiplatelet (DAPT) therapy with P2Y12 inhibitors …

Ticagrelor in patients with acute coronary syndromes and stroke: interpretation of subgroups in clinical trials

SK James, KS Pieper, CP Cannon, RF Storey… - Stroke, 2013 - Am Heart Assoc
1478 Stroke May 2013 significant increase in prespecified bleeding events. In fact, despite
the more potent antithrombotic effect, the risk of intracranial hemorrhage or fatal stroke was …