Galanin and the galanin antagonist M40 do not change fat intake in a fat-chow choice paradigm in rats

RL Corwin, PM Rowe… - American Journal of …, 1995 - journals.physiology.org
The neuropeptide galanin has been proposed to play a role in the regulation of fat intake.
The purpose of the present investigation was to determine if galanin and the galanin …

Impact of a galanin antagonist on exogenous galanin and natural patterns of fat ingestion

SF Leibowitz, T Kim - Brain research, 1992 - Elsevier
The peptide galanin (GAL) has a potent stimulatory effect on fat ingestion after
administration into the hypothalamic paraventricular nucleus (PVN). This study examined a …

Galanin receptor antagonists decrease fat preference in Brattleboro rat

M Odorizzi, B Fernette, E Angel, C Burlet, P Tankosic… - …, 2002 - Elsevier
The Brattleboro rat eats spontaneously 46% of its diet per day in fat when given a choice of
carbohydrate, protein and fat. An overexpression of galanin (GAL) has been also observed …

The effects on feeding of galanin and M40 when injected into the nucleus of the solitary tract, the lateral parabrachial nucleus, and the third ventricle

FH Koegler, DA York, GA Bray - Physiology & behavior, 1999 - Elsevier
Several reports indicate that central injection of galanin stimulates feeding, and that there is
macronutrient specificity in this response. In addition, the galanin receptor antagonist, M40 …

Hypothalamic galanin: control by signals of fat metabolism

J Wang, A Akabayashi, HJ Yu, J Dourmashkin… - Brain research, 1998 - Elsevier
The peptide, galanin (GAL), is known to stimulate eating behavior, reduce energy
expenditure and affect the release of metabolic hormones. Further, the activity of this peptide …

Centrally administered galanin‐like peptide modifies food intake in the rat: a comparison with galanin

CB Lawrence, FMH Baudoin… - Journal of …, 2002 - Wiley Online Library
Galanin‐like peptide (GALP) is a recently identified neuropeptide that shares sequence
homology with the orexigenic neuropeptide, galanin. In contrast to galanin, GALP is reported …

Feeding behaviour in galanin knockout mice supports a role of galanin in fat intake and preference

AC Adams, JC Clapham, D Wynick… - Journal of …, 2008 - Wiley Online Library
It has been widely suggested that saturated fat consumption has fuelled the current obesity
epidemic. Macronutrient choices appear to be important not only as potential factors …

Effect of galanin on food intake in rats: involvement of lateral and ventromedial hypothalamic sites

RR Schick, S Samsami… - American Journal …, 1993 - journals.physiology.org
Galanin has previously been reported to elicit feeding in satiated animals when injected into
the hypothalamic paraventricular nucleus. It is not known, however, 1) whether this action is …

Regulation and effects of hypothalamic galanin: relation to dietary fat, alcohol ingestion, circulating lipids and energy homeostasis

SF Leibowitz - Neuropeptides, 2005 - Elsevier
Galanin (GAL) is known to stimulate feeding behavior. This peptide has different properties
and functions from other feeding stimulants, eg, neuropeptide Y and agouti-related protein …

PVN galanin increases fat storage and promotes obesity by causing muscle to utilize carbohydrate more than fat

R Yun, JT Dourmashkin, J Hill, EC Gayles, SK Fried… - Peptides, 2005 - Elsevier
To understand the function of the feeding-stimulatory peptide, galanin (GAL), in eating and
body weight regulation, the present experiments tested the effects of both acute and chronic …