Autonomic nervous system-mediated effects of galanin-like peptide on lipid metabolism in liver and adipose tissue

S Hirako, N Wada, H Kageyama, F Takenoya… - Scientific reports, 2016 - nature.com
Galanin-like peptide (GALP) is a neuropeptide involved in the regulation of feeding behavior
and energy metabolism in mammals. While a weight loss effect of GALP has been reported …

Galanin receptor antagonists M40 and C7 block galanin-induced feeding

JN Crawley, JK Robinson, T Bartfai - Brain research, 1993 - Elsevier
Two peptide antagonists of the galanin receptor, M40 (galanin [1–13]-Pro-Pro-[Ala-Leu] 2-
Ala amide) and C7 (galanin [1–13]-spantide amide), significantly inhibited galanin-induced …

Altered response to metabolic challenges in mice with genetically targeted deletions of galanin-like peptide

HM Dungan Lemko, DK Clifton… - American Journal of …, 2008 - journals.physiology.org
Galanin-like peptide (GALP) is expressed in the arcuate nucleus and is implicated in the
neuroendocrine regulation of metabolism and reproduction. To investigate the physiological …

Galanin in the hypothalamus raises dopamine and lowers acetylcholine release in the nucleus accumbens: a possible mechanism for hypothalamic initiation of …

P Rada, GP Mark, BG Hoebel - Brain research, 1998 - Elsevier
Rats were prepared with two implanted guide shafts, one for microdialysis to measure
extracellular dopamine (DA) and acetylcholine (ACh) in the posterior, medial nucleus …

Analysis of the contribution of galanin receptors 1 and 2 to the central actions of galanin-like peptide

SM Krasnow, JG Hohmann, A Gragerov… - …, 2004 - karger.com
Galanin-like peptide (GALP) shares partial sequence identity with galanin and exhibits
agonistic activity at two of the galanin receptor subtypes (GALR1 and GALR2) in vitro. The …

Stimulation of food intake after central galanin is associated with arcuate nucleus activation and does not differ between genetically selected low and high body weight …

CJ Hagen, BA Newmyer, RI Webster, ER Gilbert… - Neuropeptides, 2013 - Elsevier
Galanin, a 29 residue peptide found in the hypothalamus, causes orexigenic effects in a
variety of species. In the present study, we investigated appetite-associated effects of …

Galanin-like peptide stimulates food intake via activation of neuropeptide Y neurons in the hypothalamic dorsomedial nucleus of the rat

M Kuramochi, T Onaka, D Kohno, S Kato… - Endocrinology, 2006 - academic.oup.com
Galanin-like peptide (GALP), a 29-amino-acid neuropeptide, is located in the hypothalamic
arcuate nucleus (ARC), binds to galanin receptor subtype 2, and induces food intake upon …

[HTML][HTML] The GalR2 galanin receptor mediates galanin-induced jejunal contraction, but not feeding behavior, in the rat: differentiation of central and peripheral effects …

S Wang, L Ghibaudi, T Hashemi, C He, C Strader… - FEBS letters, 1998 - Elsevier
The neuropeptide galanin mediates a diverse array of physiological functions through
activation of specific receptors. Roles of the three recently cloned galanin receptors (GalRs) …

Regulation of feeding behavior and energy metabolism by galanin-like peptide (GALP): A novel strategy to fight against obesity

F Takenoya, S Hirako, N Wada… - Current …, 2018 - ingentaconnect.com
Galanin-like peptide (GALP) is composed of 60 amino acid residues and its sequence is
highly homologous across species. GALP is produced in the hypothalamic arcuate nucleus …

Differential patterns of Fos induction in the hypothalamus of the rat following central injections of galanin-like peptide and galanin

GS Fraley, I Shimada, JW Baumgartner… - …, 2003 - academic.oup.com
Galanin and its newly discovered relative galanin-like peptide (GALP) are neuropeptides
that are implicated in the neuroendocrine regulation of body weight and reproduction. GALP …