Metabolic effects of galanin injections into the paraventricular nucleus of the hypothalamus

JA Menéndez, DM Atrens, SF Leibowitz - Peptides, 1992 - Elsevier
The metabolic effects of single injections of galanin into the paraventricular nucleus of the
hypothalamus (PVN) were investigated in an open-circuit calorimeter. Wistar rats were …

Regulation of galanin gene expression in the hypothalamic paraventricular nucleus of the obese Zucker rat by manipulation of dietary macronutrients

JG Mercer, CB Lawrence, T Atkinson - Molecular brain research, 1996 - Elsevier
Lean and obese male Zucker rats were fed high fat (72% of energy as fat), high
carbohydrate (66% of energy as carbohydrate) or intermediate diets for 4 weeks …

Loss-of-function mutation of the galanin gene is associated with perturbed islet function in mice

B Ahrén, G Pacini, D Wynick, N Wierup… - Endocrinology, 2004 - academic.oup.com
The neuropeptide galanin is expressed in sympathetic nerve terminals that surround islet
cells and inhibits insulin secretion. To explore its role for islet function, we studied mice with …

[HTML][HTML] Expression cloning of a rat hypothalamic galanin receptor coupled to phosphoinositide turnover

KE Smith, C Forray, MW Walker, KA Jones… - Journal of Biological …, 1997 - ASBMB
The neuropeptide galanin is widely distributed throughout the central and peripheral
nervous systems and participates in the regulation of processes such as nociception …

L‐Ala‐substituted rat galanin analogs distinguish between hypothalamic and jejunal galanin receptor subtypes

A JURÉUS, ÜLO LANGEL… - The Journal of peptide …, 1997 - Wiley Online Library
In order to explore which amino acids or which blocks of amino acids in the 29 amino acid
neuropeptide galanin are important for recognition of the endogenous ligand by galanin …

Activation of the sympathetic nervous system by galanin-like peptide—a possible link between leptin and metabolism

KR Hansen, SM Krasnow, MA Nolan, GS Fraley… - …, 2003 - academic.oup.com
The effects of leptin upon body weight (BW) cannot be explained by its anorectic actions
alone. Part of the metabolic changes elicited by leptin includes sympathetic nervous system …

Galanin receptor-mediated inhibition of glutamate release in the arcuate nucleus of the hypothalamus

GA Kinney, PJ Emmerson, RJ Miller - Journal of Neuroscience, 1998 - Soc Neuroscience
It is thought that galanin, a 29 amino acid neuropeptide, is involved in various neuronal
functions, including the regulation of food intake and hormone release. Consistent with this …

Distribution, regulation and role of hypothalamic galanin systems: renewed interest in a pleiotropic peptide family.

AL Gundlach, TCD Burazin… - Clinical & Experimental …, 2001 - search.ebscohost.com
Examines the effects of hypothalamic galanin systems on hypothalamic neurons.
Distribution of galanin and galanin receptor systems in hypothalamus; Inhibitory effects of …

Regional stimulatory and inhibitory effects of guanine nucleotides on [125I] galanin binding in rat brain: relationship with the rate of occupancy of galanin receptors by …

I Lagny-Pourmir, J Epelbaum - Neuroscience, 1992 - Elsevier
Galanin has been shown to stimulate feeding or modulate neuroendocrine secretions when
administered centrally. In the present work, using quantitative autoradiography, we …

Galanin antagonist increases insulin resistance by reducing glucose transporter 4 effect in adipocytes of rats

L Guo, M Shi, L Zhang, G Li, L Zhang, H Shao… - General and …, 2011 - Elsevier
Seeing that galanin increases animal body weight on the conditions of inhibiting insulin
secretion and animals with metabolic disorder of galanin easily suffer from diabetes, we …