Galanin-like peptide in the brain: effects on feeding, energy metabolism and reproduction

H Kageyama, F Takenoya, T Kita, T Hori, JL Guan… - Regulatory peptides, 2005 - Elsevier
The hypothalamus plays an important role in the regulation of feeding behavior, energy
metabolism and reproduction. A novel peptide containing 60 amino acid peptide and a non …

Galanin knockout mice show disturbances in ethanol consumption and expression of hypothalamic peptides that stimulate ethanol intake

O Karatayev, J Baylan, V Weed… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Background: There is growing evidence suggesting that hypothalamic galanin (GAL), which
is known to stimulate intake of a fat‐rich diet, has a role in promoting the consumption of …

Differential effects of enterostatin, galanin and opioids on high-fat diet consumption

C Barton, L Lin, DA York, GA Bray - Brain research, 1995 - Elsevier
Enterostatin, the activation peptide of pancreatic procolipase, suppresses high-fat diet
consumption both centrally and peripherally. κ-opioid agonists are also known to stimulate …

Neuroendocrine profiles in galanin-overexpressing and knockout mice

JG Hohmann, SM Krasnow, DN Teklemichael… - …, 2003 - karger.com
The peptide galanin has been implicated in the neuroendocrine regulation of reproduction
and energy balance. To gain more insight into the functional significance of galanin in these …

Loss-of-function mutation of the galanin gene is associated with perturbed islet function in mice

B Ahrén, G Pacini, D Wynick, N Wierup… - Endocrinology, 2004 - academic.oup.com
The neuropeptide galanin is expressed in sympathetic nerve terminals that surround islet
cells and inhibits insulin secretion. To explore its role for islet function, we studied mice with …

L‐Ala‐substituted rat galanin analogs distinguish between hypothalamic and jejunal galanin receptor subtypes

A JURÉUS, ÜLO LANGEL… - The Journal of peptide …, 1997 - Wiley Online Library
In order to explore which amino acids or which blocks of amino acids in the 29 amino acid
neuropeptide galanin are important for recognition of the endogenous ligand by galanin …

Expression cloning of a rat hypothalamic galanin receptor coupled to phosphoinositide turnover

KE Smith, C Forray, MW Walker, KA Jones… - Journal of Biological …, 1997 - ASBMB
The neuropeptide galanin is widely distributed throughout the central and peripheral
nervous systems and participates in the regulation of processes such as nociception …

Galanin receptor-mediated inhibition of glutamate release in the arcuate nucleus of the hypothalamus

GA Kinney, PJ Emmerson, RJ Miller - Journal of Neuroscience, 1998 - Soc Neuroscience
It is thought that galanin, a 29 amino acid neuropeptide, is involved in various neuronal
functions, including the regulation of food intake and hormone release. Consistent with this …

Distribution, regulation and role of hypothalamic galanin systems: renewed interest in a pleiotropic peptide family.

AL Gundlach, TCD Burazin… - Clinical & Experimental …, 2001 - search.ebscohost.com
Examines the effects of hypothalamic galanin systems on hypothalamic neurons.
Distribution of galanin and galanin receptor systems in hypothalamus; Inhibitory effects of …

Obesity and endocrine dysfunction in mice with deletions of both neuropeptide Y and galanin

JG Hohmann, DN Teklemichael… - … and cellular biology, 2004 - Am Soc Microbiol
Neuropeptide Y (NPY) and galanin have both been implicated in the regulation of body
weight, yet mice bearing deletions of either of these molecules have unremarkable …