Bioaccumulation plays a vital role in understanding the fate of a substance in the
environment and is key to the regulation of chemicals in several jurisdictions. The current …

Bioaccumulation, the accumulation of a chemical in an organism relative to its level in the
ambient medium, is of major environmental concern. Thus, monitoring chemical …

The identification and regulation of substances that combine persistence, bioaccumulation
potential, and toxicity (“PBT” substances) is one central aspect of the European chemical …

Bioaccumulation and biomagnification of chemicals in biota may be a prerequisite for
adverse effects in individuals, species, and ecosystems. From disastrous events posed by …

Bioaccumulation is one of the three criteria for the PBT assessment of chemicals, where P
stands for persistence, B for bioaccumulation, and T for toxicity, which is a cornerstone for …

REACH (registration, evaluation, authorisation and restriction of chemicals) regulation
requires that all the chemicals produced or imported in Europe above 1 tonne/year are …

Abstract Persistent, Bioaccumulative and Toxic (PBT) and very Persistent and very
Bioaccumulative (vPvB) are regulatory hazard categories that have been set to manage the …

Bioaccumulation assessments conducted by regulatory agencies worldwide use a variety of
methods, types of data, metrics, and categorization criteria. Lines of evidence (LoE) for …

Scientists from academia, industry, and government reviewed current international
regulations for the screening of commercial chemicals for bioaccumulation in the context of …

It has been asserted that, when screening chemicals for bioaccumulation potential,
molecular size cutoff criteria (or indicators) can be applied above which no, or limited …