G-protein-coupled receptors (GPCRs) comprise the largest family of transmembrane
receptors in the human genome that respond to a plethora of signals, including …

Recently, many G-protein-coupled receptors (GPCRs) have been demonstrated to form
constitutive dimers consisting of identical or distinct monomeric subunits. The discovery of …

G protein-coupled receptors (GPCRs) are cell surface receptors that mediate physiological
responses to a diverse array of stimuli. GPCRs have traditionally been thought to act as …

The classical idea that G‐protein‐coupled receptors (GPCRs) function as monomeric
entities has been unsettled by the emerging concept of GPCR dimerization. Recent findings …

G protein-coupled receptors (GPCRs) can exist as dimers or as larger oligomeric clusters
that enable intercommunication between different receptor protomers within the same …

Although highly controversial just a few years ago, the idea that G‐protein‐coupled
receptors (GPCRs) may undergo homo‐oligomerization or hetero‐oligomerization has …

With an ever-expanding need for reliable therapeutic agents that are highly effective and
exhibit minimal deleterious side effects, a greater understanding of the mechanisms …

In the last four to five years, the view that G protein–coupled receptors (GPCRs) function as
monomeric proteins has been challenged by numerous studies, which suggests that GPCRs …

Although classical models predict that G-protein-coupled receptors (GPCRs) function as
monomers, several recent studies acknowledge that GPCRs exist as dimeric or oligomeric …

Hormones, sensory stimuli, neurotransmitters and chemokines signal by activating G-protein-
coupled receptors (GPCRs)[1]. Although GPCRs are thought to function as monomers, they …