Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
J Salomon, DR Flower - BMC bioinformatics, 2006 - Springer
Background Modelling the interaction between potentially antigenic peptides and Major
Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell …
Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell …
Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian prior
Background Experts in peptide: MHC binding studies are often able to estimate the impact of
a single residue substitution based on a heuristic understanding of amino acid similarity in …
a single residue substitution based on a heuristic understanding of amino acid similarity in …
A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach
The identification of MHC class II restricted peptide epitopes is an important goal in
immunological research. A number of computational tools have been developed for this …
immunological research. A number of computational tools have been developed for this …
Automated benchmarking of peptide-MHC class I binding predictions
Motivation: Numerous in silico methods predicting peptide binding to major
histocompatibility complex (MHC) class I molecules have been developed over the last …
histocompatibility complex (MHC) class I molecules have been developed over the last …
Efficient peptide–MHC-I binding prediction for alleles with few known binders
Motivation: In silico methods for the prediction of antigenic peptides binding to MHC class I
molecules play an increasingly important role in the identification of T-cell epitopes …
molecules play an increasingly important role in the identification of T-cell epitopes …
Predicting MHC class I epitopes in large datasets
K Roomp, I Antes, T Lengauer - Bmc Bioinformatics, 2010 - Springer
Background Experimental screening of large sets of peptides with respect to their MHC
binding capabilities is still very demanding due to the large number of possible peptide …
binding capabilities is still very demanding due to the large number of possible peptide …
Examining the independent binding assumption for binding of peptide epitopes to MHC-I molecules
Motivation: Various methods have been proposed to predict the binding affinities of peptides
to Major Histocompatibility Complex class I (MHC-I) molecules based on experimental …
to Major Histocompatibility Complex class I (MHC-I) molecules based on experimental …
MetaMHC: a meta approach to predict peptides binding to MHC molecules
X Hu, W Zhou, K Udaka, H Mamitsuka… - Nucleic acids …, 2010 - academic.oup.com
As antigenic peptides binding to major histocompatibility complex (MHC) molecules is the
prerequisite of cellular immune responses, an accurate computational predictor will be of …
prerequisite of cellular immune responses, an accurate computational predictor will be of …
NetMHCcons: a consensus method for the major histocompatibility complex class I predictions
A key role in cell-mediated immunity is dedicated to the major histocompatibility complex
(MHC) molecules that bind peptides for presentation on the cell surface. Several in silico …
(MHC) molecules that bind peptides for presentation on the cell surface. Several in silico …
Learning MHC I—peptide binding
Motivation and results: Motivated by the ability of a simple threading approach to predict
MHC I—peptide binding, we developed a new and improved structure-based model for …
MHC I—peptide binding, we developed a new and improved structure-based model for …