Heteroatom (B, N, P, and S)-doped cyclodextrin as a hydroxyurea (HU) drug nanocarrier: a computational approach

LE Afahanam, H Louis, I Benjamin, TE Gber, IJ Ikot… - ACS …, 2023 - ACS Publications
Theoretical examination of hydroxyurea adsorption capabilities toward the cyclodextrin
surface for proper drug delivery systems was carried out utilizing DFT simulations. The study …

Cyclodextrin nanoparticles for diagnosis and potential cancer therapy: A systematic review

A Karthic, A Roy, J Lakkakula, S Alghamdi… - Frontiers in Cell and …, 2022 - frontiersin.org
Cancer is still one of the world's deadliest health concerns. As per latest statistics, lung,
breast, liver, prostate, and cervical cancers are reported topmost worldwide. Although …

Stimuli-responsive cyclodextrin-based nanoplatforms for cancer treatment and theranostics

X Yao, J Mu, L Zeng, J Lin, Z Nie, X Jiang… - Materials Horizons, 2019 - pubs.rsc.org
Cyclodextrins (CDs) with highly branched hydroxyl moieties and hydrophobic cavities, have
been widely employed as building blocks for the construction of CD-based nanoplatforms …

Unveiling the intricate supramolecular chemistry of γ-cyclodextrin-epigallocatechin gallate inclusion complexes

P Kumar, VK Bhardwaj, R Purohit - Industrial & Engineering …, 2024 - ACS Publications
Green tea's main polyphenol, epigallocatechin-gallate (EgCg), garners attention for diverse
health-promoting properties. Due to the limited bioavailability of EgCg, drug formulation …

Advances in the development of cyclodextrin-based nanogels/microgels for biomedical applications: Drug delivery and beyond

F Topuz, T Uyar - Carbohydrate Polymers, 2022 - Elsevier
Nanogels/microgels are swollen cross-linked polymer networks with tunable
physicochemical properties and are commonly employed for the effective delivery of …

Pharmaceutical applications of cyclodextrins and their derivatives

P Dhiman, M Bhatia - Journal of Inclusion Phenomena and Macrocyclic …, 2020 - Springer
Cyclodextrins (CDs) are abundantly explored in the field of medicines for the design of
various types of drug delivery systems. They are cyclic oligosaccharides carrying α (1, 4) …

Cyclodextrin: A prospective nanocarrier for the delivery of antibacterial agents against bacteria that are resistant to antibiotics

P Saha, MR Rafe - Heliyon, 2023 - cell.com
Supramolecular chemistry introduces us to the macrocyclic host cyclodextrin, which has a
hydrophobic cavity. The hydrophobic cavity has a higher affinity for hydrophobic guest …

Cyclodextrin‐based multistimuli‐responsive supramolecular assemblies and their biological functions

YM Zhang, YH Liu, Y Liu - Advanced Materials, 2020 - Wiley Online Library
Cyclodextrins (CDs), which are a class of cyclic oligosaccharides extracted from the
enzymatic degradation of starch, are often utilized in molecular recognition and assembly …

Cyclodextrin-based host–guest supramolecular hydrogels for local drug delivery

G Fang, X Yang, S Chen, Q Wang, A Zhang… - Coordination Chemistry …, 2022 - Elsevier
Cyclodextrin (CD) is one of the most versatile substances produced by nature and can form
supramolecular hydrogels with polymers or small molecules based on non-covalent …

Novel pH-triggered doxorubicin-releasing nanoparticles self-assembled by functionalized β-cyclodextrin and amphiphilic phthalocyanine for anticancer therapy

K Zheng, X Liu, H Liu, D Dong, L Li… - … Applied Materials & …, 2021 - ACS Publications
Cyclodextrins (CDs), as pharmaceutical excipients with excellent biocompatibility, non-
immunogenicity, and low toxicity in vivo, are widely used to carry drugs by forming inclusion …