Semaglutide in obesity: unmet needs in men

M Jensterle, M Rizzo, A Janež - Diabetes Therapy, 2023 - Springer
Global average data suggest that the prevalence of male obesity is increasing and that its
prevalence in some regions of Western Europe, Japan, China, Korea and USA is higher …

Efficacy of semaglutide in overweight and obese patients with type 1 diabetes

SK Garg, G Kaur, Z Haider, E Rodriquez… - Diabetes Technology …, 2024 - liebertpub.com
Introduction: More than two-thirds of patients with type 1 diabetes (T1D) are overweight (OW)
and/or obese (OB) in the USA and Western Europe, resulting in insulin resistance as in type …

Semaglutide 2.4 mg for the treatment of obesity: key elements of the STEP trials 1 to 5

RF Kushner, S Calanna, M Davies, D Dicker… - …, 2020 - Wiley Online Library
Objective The obesity epidemic is a public health concern, warranting further research into
pharmacological treatments for weight management (WM) as an adjunct to lifestyle …

Real-world use of oral versus subcutaneous semaglutide in a cohort of type 2 diabetic patients: which option to which patient?

C Formichi, W Baronti, G de Gennaro… - Journal of …, 2024 - Springer
Purpose To evaluate the variables influencing the therapeutic choice toward oral versus
subcutaneous semaglutide in a cohort of diabetic subjects. Methods We retrospectively …

Semaglutide added to basal insulin in type 2 diabetes (SUSTAIN 5): a randomized, controlled trial

HW Rodbard, I Lingvay, J Reed… - The Journal of …, 2018 - academic.oup.com
Context Combination therapy with insulin and glucagon-like peptide-1 receptor agonists
(GLP-1RAs) is important for treating type 2 diabetes (T2D). This trial assesses the efficacy …

Semaglutide 2.4 mg clinical outcomes in patients with obesity or overweight in a real‐world setting: A 6‐month retrospective study in the United States (SCOPE)

A Ruseva, W Michalak, Z Zhao… - Obesity Science & …, 2024 - Wiley Online Library
Background Management guidelines for obesity suggest maintaining a minimum of 5% body
weight reduction to help prevent or lower the risk of developing conditions such as …

Semaglutide 2.4 mg: the latest GLP-1RA approved for obesity

R Villela, R Correa - Journal of Investigative Medicine, 2022 - journals.sagepub.com
Overweight and obesity are one of the most relevant health factors; according to the WHO,
39% of people globally are overweight and 13% obese. 1 Body weight loss of 3%–5% has …

Semaglutide for obesity: four STEPs forward, but more to come

DH Ryan - The Lancet Diabetes & Endocrinology, 2021 - thelancet.com
Semaglutide 2· 4 mg once weekly, an anti-obesity medication now submitted to regulators
across the USA and Europe, is generating much excitement and attention about the amount …

Semaglutide for the treatment of overweight and obesity: a review

NC Bergmann, MJ Davies, I Lingvay… - Diabetes, Obesity and …, 2023 - Wiley Online Library
Obesity is a chronic, relapsing disease associated with multiple complications and a
substantial morbidity, mortality and health care burden. Pharmacological treatments for …

Weight loss outcomes associated with semaglutide treatment for patients with overweight or obesity

W Ghusn, A De la Rosa, D Sacoto… - JAMA Network …, 2022 - jamanetwork.com
Importance No retrospective cohort study has assessed the effectiveness of semaglutide at
doses used in randomized clinical trials to treat obesity (ie, 1.7 and 2.4 mg). Objective To …