[HTML][HTML] Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens
Fungal infections are a growing public health concern, and an increasingly important cause
of human mortality, with Candida species being amongst the most frequently encountered of …
of human mortality, with Candida species being amongst the most frequently encountered of …
Candida morphogenesis and host–pathogen interactions
M Whiteway, U Oberholzer - Current opinion in microbiology, 2004 - Elsevier
The human fungal pathogen Candida albicans has many morphological forms. Recent
advances in genomics and cell biology are providing an improved understanding of the …
advances in genomics and cell biology are providing an improved understanding of the …
Regulatory mechanisms controlling morphology and pathogenesis in Candida albicans
D Kadosh - Current opinion in microbiology, 2019 - Elsevier
Highlights•There is a strong association between C. albicans morphology and virulence.•C.
albicans morphology control mechanisms may serve as important antifungal …
albicans morphology control mechanisms may serve as important antifungal …
Coevolution of morphology and virulence in Candida species
DS Thompson, PL Carlisle, D Kadosh - Eukaryotic cell, 2011 - Am Soc Microbiol
Many of the major human fungal pathogens are known to undergo morphological changes,
which in certain cases are associated with virulence. Although there has been an intense …
which in certain cases are associated with virulence. Although there has been an intense …
[HTML][HTML] The Missing Link between Candida albicans Hyphal Morphogenesis and Host Cell Damage
Fungal pathogens are more commonly associated with morbidity and mortality than
generally appreciated. In fact, a significant portion of the world population is infected by …
generally appreciated. In fact, a significant portion of the world population is infected by …
The regulation of hyphae growth in Candida albicans
In the last decades, Candida albicans has served as the leading causal agent of life-
threatening invasive infections with mortality rates approaching 40% despite treatment …
threatening invasive infections with mortality rates approaching 40% despite treatment …
Potential targets for antifungal drug discovery based on growth and virulence in Candida albicans
X Li, Y Hou, L Yue, S Liu, J Du… - Antimicrobial agents and …, 2015 - Am Soc Microbiol
Fungal infections, especially infections caused by Candida albicans, remain a challenging
problem in clinical settings. Despite the development of more-effective antifungal drugs, their …
problem in clinical settings. Despite the development of more-effective antifungal drugs, their …
Candida Biofilms: An Update on Developmental Mechanisms and Therapeutic Challenges
PP de Barros, RD Rossoni, CM de Souza, L Scorzoni… - Mycopathologia, 2020 - Springer
Fungi of the genus Candida are important etiological agents of superficial and life-
threatening infections in individuals with a compromised immune system. One of the main …
threatening infections in individuals with a compromised immune system. One of the main …
[HTML][HTML] Recent advances in understanding Candida albicans hyphal growth
RA Arkowitz, M Bassilana - F1000Research, 2019 - ncbi.nlm.nih.gov
Morphological changes are critical for the virulence of a range of plant and human fungal
pathogens. Candida albicans is a major human fungal pathogen whose ability to switch …
pathogens. Candida albicans is a major human fungal pathogen whose ability to switch …
Targeting Candida albicans filamentation for antifungal drug development
Candida albicans remains the main etiological agent of candidiasis, as this otherwise
normal commensal of humans is capable of causing active infection in immune-and …
normal commensal of humans is capable of causing active infection in immune-and …