Statins possess an excellent safety profile and are generally well tolerated when
administered in the standard once-daily dosing regimen. A small percentage of patients …

The purpose of this study was to determine the efficacy of rosuvastatin dosed once a week in
patients with a previous statin adverse event. Rosuvastatin once a week was tolerated by 37 …

The aim of this study was to evaluate the efficacy of rosuvastatin twice weekly in 40 patients
intolerant to daily statins. Rosuvastatin twice weekly alone or added to other lipid-lowering …

BACKGROUND: Many patients who could benefit from hydroxymethylglutaryl coenzyme-A
reductase inhibitors (statins) are unable to take statins because of myalgias while taking …

Statins are normally administered for the treatment of dyslipidemia on a daily basis. This
standard dosing regimen is well tolerated by most patients. Occasionally, patients …

Objective: To examine the efficacy and tolerability of rosuvastatin 5 mg at daily and non-daily
dosing regimens. Research design and methods: A retrospective survey was conducted at …

BACKGROUND: Statins are the treatment of choice for lowering LDL-C levels and reducing
cardiovascular events. They have a remarkable safety profile, although some patients do not …

Results 117 (52.7%) patients completed this study. When the target LDL cholesterol level
was< 100 mg/dL, there was no significant difference in the target attainment rate between …

The safety and tolerability of rosuvastatin were assessed (as of August 2003) using data
from 12,400 patients who received 5 to 40 mg of rosuvastatin in a multinational phase II/III …

Statins are critical medications to prevent and treat cardiovascular disease2 and they are
generally very well tolerated. In some instances, however, statin intolerance may limit use of …