Genome-wide profiling of papillary thyroid cancer identifies MUC1 as an independent prognostic marker
VB Wreesmann, EM Sieczka, ND Socci, M Hezel… - Cancer research, 2004 - AACR
Clinicopathological variables used at present for prognostication and treatment selection for
papillary thyroid carcinomas (PTCs) do not uniformly predict tumor behavior, necessitating …
papillary thyroid carcinomas (PTCs) do not uniformly predict tumor behavior, necessitating …
The cytoplasmic expression of MUC1 in papillary thyroid carcinoma of different histological variants and its correlation with cyclin D1 overexpression
A Abrosimov, V Saenko, S Meirmanov… - Endocrine …, 2007 - Springer
This study addressed the immunohistochemical expression of MUC1 in papillary thyroid
carcinoma (PTC) of different histotypes, sizes, and morphological features of …
carcinoma (PTC) of different histotypes, sizes, and morphological features of …
Muc-1 expression may help characterize thyroid nodules but does not predict patients' outcome
EC Morari, JR Silva, ACT Guilhen, LL Cunha… - Endocrine …, 2010 - Springer
Our purpose was to evaluate MUC1 clinical utility in the diagnosis and prognosis of thyroid
cancer patients. We studied the protein expression of MUC1 in 289 thyroid carcinomas and …
cancer patients. We studied the protein expression of MUC1 in 289 thyroid carcinomas and …
Papillary and follicular thyroid carcinomas show distinctly different microarray expression profiles and can be distinguished by a minimum of five genes
MA Aldred, Y Huang, S Liyanarachchi… - Journal of Clinical …, 2004 - ascopubs.org
Purpose We have previously conducted independent microarray expression analyses of the
two most common types of nonmedullary thyroid carcinoma, namely papillary thyroid …
two most common types of nonmedullary thyroid carcinoma, namely papillary thyroid …
MUC1 plays a role in tumor maintenance in aggressive thyroid carcinomas
KN Patel, E Maghami, VB Wreesmann, AR Shaha… - Surgery, 2005 - Elsevier
BACKGROUND: We recently identified MUC1 as a target driving selection for 1q21
amplification and validated it as an independent marker of aggressive behavior in thyroid …
amplification and validated it as an independent marker of aggressive behavior in thyroid …
Expression of the membrane mucins MUC4 and MUC15, potential markers of malignancy and prognosis, in papillary thyroid carcinoma
Background: Papillary thyroid carcinoma (PTC) is the most frequent carcinoma of the thyroid
gland and has a relatively good prognosis. However, it is important to identify PTC …
gland and has a relatively good prognosis. However, it is important to identify PTC …
Gene expression and the biological phenotype of papillary thyroid carcinomas
L Delys, V Detours, B Franc, G Thomas, T Bogdanova… - Oncogene, 2007 - nature.com
The purpose of this paper is to correlate the molecular phenotype of papillary thyroid
carcinoma (PTC) to their biological pathology. We hybridized 26 PTC on microarrays and …
carcinoma (PTC) to their biological pathology. We hybridized 26 PTC on microarrays and …
Development of prognostic signatures for intermediate-risk papillary thyroid cancer
Abstract Background The incidence of Papillary thyroid carcinoma (PTC), the most common
type of thyroid malignancy, has risen rapidly worldwide. PTC usually has an excellent …
type of thyroid malignancy, has risen rapidly worldwide. PTC usually has an excellent …
MUC1 oncoprotein promotes refractoriness to chemotherapy in thyroid cancer cells
M Siragusa, M Zerilli, F Iovino, MG Francipane… - Cancer research, 2007 - AACR
Overexpression of MUC1 oncoprotein is frequently observed in cancer and contributes to
confer resistance to genotoxic agents. Papillary, follicular, and anaplastic thyroid carcinomas …
confer resistance to genotoxic agents. Papillary, follicular, and anaplastic thyroid carcinomas …
Genetic landscape of papillary thyroid carcinoma in the Chinese population
J Liang, W Cai, D Feng, H Teng, F Mao… - The Journal of …, 2018 - Wiley Online Library
Improvement in the clinical outcome of human cancers requires characterization of the
genetic alterations underlying their pathogenesis. Large‐scale genomic and transcriptomic …
genetic alterations underlying their pathogenesis. Large‐scale genomic and transcriptomic …
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