To investigate the association of single-nucleotide polymorphisms (SNPs) in exon 17 of the
insulin receptor (INSR) gene with insulin resistance and INSR β-subunit expression in …

The insulin receptor (INSR), which is an indispensable component of the insulin-signalling
pathway, could be a plausible candidate gene for polycystic ovary syndrome (PCOS). This …

OBJECTIVE: To investigate several single nucleotide polymorphisms (SNPs) in the insulin
receptor (INSR) gene that have significant associations with pathogenesis of polycystic …

OBJECTIVE: To assess the association between the single nucleotide polymorphism of the
insulin receptor (INSR) gene and polycystic ovary syndrome (PCOS) in a Korean population …

Background Polycystic ovary syndrome (PCOS) is a complex disease having both genetic
and environmental components. Candidate genes with insulin metabolism have been …

Background Insulin and its receptor (INSR) have been implicated in the etiology of the
polycystic ovarian syndrome (PCOS). Here, we investigate the association between INSR …

Objective To investigate the correlation of C/T single nucleotide polymorphism at exon 17 in
tyrosine kinase domain of insulin receptor gene with polycystic ovary syndrome (PCOS) …

Background: Polycystic ovarian syndrome (PCOS) is a complex, heterogeneous disorder of
uncertain etiology with strong genetic background. Insulin resistance is present in the …

Objective To assess whether the insulin receptor (INSR) gene contributes to genetic
susceptibility to polycystic ovary syndrome (PCOS) in a Japanese population. Study design …

Objective Polycystic ovary syndrome (PCOS) is a multigenic disorder, and insulin resistance
is one of its hallmark features. Polymorphisms in exon 17 of insulin receptor (INSR) gene are …