Braun lipoprotein (Lpp) contributes to virulence of yersiniae: potential role of Lpp in inducing bubonic and pneumonic plague

J Sha, SL Agar, WB Baze, JP Olano, AA Fadl… - Infection and …, 2008 - Am Soc Microbiol
Yersinia pestis evolved from Y. pseudotuberculosis to become the causative agent of
bubonic and pneumonic plague. We identified a homolog of the Salmonella enterica serovar …

Immunization of mice with YscF provides protection from Yersinia pestis infections

JS Matson, KA Durick, DS Bradley, ML Nilles - BMC microbiology, 2005 - Springer
Background Yersinia pestis, the causative agent of plague, is a pathogen with a tremendous
ability to cause harm and panic in populations. Due to the severity of plague and its potential …

Generation of Yersinia pestis Attenuated Strains by Signature-Tagged Mutagenesis in Search of Novel Vaccine Candidates

Y Flashner, E Mamroud, A Tidhar, R Ber… - Infection and …, 2004 - Am Soc Microbiol
In a search for novel attenuated vaccine candidates for use against Yersinia pestis, the
causative agent of plague, a signature-tagged mutagenesis strategy was used and …

Immune Response to Yersinia Outer Proteins and Other Yersinia pestis Antigens after Experimental Plague Infection in Mice

GE Benner, GP Andrews, WR Byrne… - Infection and …, 1999 - Am Soc Microbiol
There is limited information concerning the nature and extent of the immune response to the
virulence determinants of Yersinia pestis during the course of plague infection. In this study …

Progression of primary pneumonic plague: a mouse model of infection, pathology, and bacterial transcriptional activity

WW Lathem, SD Crosby, VL Miller… - Proceedings of the …, 2005 - National Acad Sciences
Although pneumonic plague is the deadliest manifestation of disease caused by the
bacterium Yersinia pestis, there is surprisingly little information on the cellular and molecular …

A hypervariable N-terminal region of Yersinia LcrV determines Toll-like receptor 2-mediated IL-10 induction and mouse virulence

A Sing, D Reithmeier-Rost, K Granfors… - Proceedings of the …, 2005 - National Acad Sciences
The virulence antigen LcrV of Yersinia enterocolitica O: 8 induces IL-10 in macrophages via
Toll-like receptor 2 (TLR2). The TLR2-active region of LcrV is localized within its N-terminal …