Natural Autophagy Activators: A Promising Strategy for Combating Photoaging

A Vikram, SK Patel, A Singh, D Pathania, RS Ray… - Phytomedicine, 2024 - Elsevier
Background Photodamage to the skin stands out as one of the most widespread epidermal
challenges globally. Prolonged exposure to sunlight containing ultraviolet radiation (UVR) …

Pharmacological activation of autophagy restores cellular homeostasis in ultraviolet-(B)-induced skin photodamage

SA Umar, NH Shahid, LA Nazir, MA Tanveer… - Frontiers in …, 2021 - frontiersin.org
Ultraviolet (UV) exposure to the skin causes photo-damage and acts as the primary
etiological agent in photo-carcinogenesis. UV-B exposure induces cellular damage and is …

Autophagy plays an essential role in ultraviolet radiation-driven skin photoaging

J Ma, Y Teng, Y Huang, X Tao, Y Fan - Frontiers in Pharmacology, 2022 - frontiersin.org
Photoaging is characterized by a chronic inflammatory response to UV light. One of the most
prominent features of cutaneous photoaging is wrinkling, which is due primarily to a loss of …

Autophagy: multiple mechanisms to protect skin from ultraviolet radiation‐driven photoaging

M Wang, P Charareh, X Lei… - Oxidative Medicine and …, 2019 - Wiley Online Library
Autophagy is an essential cellular process that maintains balanced cell life. Restriction in
autophagy may induce degenerative changes in humans. Natural or pathological aging of …

Potential therapeutic approaches through modulating the autophagy process for skin barrier dysfunction

MS Choi, YJ Chae, JW Choi, JE Chang - International journal of …, 2021 - mdpi.com
Autophagy is an attractive process to researchers who are seeking novel potential
treatments for various diseases. Autophagy plays a critical role in degrading damaged …

[HTML][HTML] Natural Autophagy Activators to Fight Age-Related Diseases

VM Mundo Rivera, JR Tlacuahuac Juárez… - Cells, 2024 - mdpi.com
The constant increase in the elderly population presents significant challenges in
addressing new social, economic, and health problems concerning this population. With …

The antiaging activities of phytochemicals in dark-colored plant foods: involvement of the autophagy-and apoptosis-associated pathways

M Luo, M Mai, W Song, Q Yuan, X Feng, E Xia… - International journal of …, 2022 - mdpi.com
In the last two decades, human life expectancy has increased by about 10 years, but this has
not been accompanied by a corresponding increase in healthy lifespan. Aging is associated …

Molecular basis of skin photoaging and therapeutic interventions by plant-derived natural product ingredients: A comprehensive review

MA Tanveer, H Rashid, SA Tasduq - Heliyon, 2023 - cell.com
Skin areas exposed to ultraviolet radiation (UV) from sunlight are more prone to photoaging
than unexposed areas evidenced by several signs which include skin dryness, irregular …

Autophagy as a targeted therapeutic approach for skin cancer: Evaluating natural and synthetic molecular interventions

ML Ali, AH Roky, SMAK Azad, AH Shaikat… - Cancer Pathogenesis …, 2024 - mednexus.org
Skin cancer, a prevalent malignancy worldwide, poses significant health concerns owing to
its increasing incidence. Autophagy, a natural cellular process, is a pivotal event in skin …

Resveratrol activates autophagy to protect the skin from UVA-induced photoaging by regulating the AMPK pathway

Y Xia, H Zhang, X Wu, Y Xu, Q Tan - 2023 - researchsquare.com
Skin photoaging is mostly caused by ultraviolet A (UVA), although active medications to
effectively counteract UVA-induced photoaging have not yet been created. Resveratrol, a …