Abstract In conscious male New Zealand rabbits, bradykinin caused dose-dependent (0.03–
1 μg/kg iv) hypotension and reflex tachycardia. After inhibition of angiotensin converting …

Bradykinin (cumulative concentrations of 0.007-0.09 μ g ml− 1) produced a dose-related, but
statistically insignificant depression of the isometric contraction of the isolated …

Biphasic or pressor responses are produced by the intravenous or intra-carotid injection of
bradykinin in anaesthetized cats and in conscious or anaesthetized dogs. The analgesic …

The effect of captopril on blood pressure and on the depressor responses to intravenously
administered bradykinin was examined in anesthetized normotensive rats during inhibition …

In urethane-anesthetized rabbits, bradykinin caused a dose-dependent hypotension. This
hypotensive response was not altered in magnitude but was inhibited in duration after …

The effect of bradykinin on postganglionic sympathetic neuroeffector transmission was
studied in superfused strips of rabbit pulmonary artery and in perfused rabbit hearts. 1. In …

Intraventricular injection of bradykinin produced a dose-dependent increase in the mean
arterial blood pressure of conscious rats. With 5 nmol of bradykinin, a dual pressor response …

1 In pithed rats, preganglionic vagal nerve stimulation (at 5 Hz) elicited a bradycardia. This
bradycardia was potentiated by the angiotensin converting enzyme inhibitor, captopril (1 mg …

Angiotensin converting enzyme (ACE) inhibitors block degradation of bradykinin and
bradykinin stimulates prostacyclin production. ACE inhibitors are reported to increase …

Vertebral and carotid artery infusions of bradykinin increased blood pressure and heart rate
in anaesthetised greyhounds. Indomethacin pretreatment abolished the pressor response to …