Epidermal stem cells are a population of somatic stem cells responsible for maintaining and
repairing the epidermis of the skin. A malfunctioning epidermal stem cell compartment …

Oil-secreting sebaceous glands (SGs) are critical for proper skin function; however, it
remains unclear how different factors act together to modulate SG stem cells. Here, we …

Skin-derived precursors (SKPs) are multipotent dermal stem cells that reside within a hair
follicle niche and that share properties with embryonic neural crest precursors. Here, we …

Aging is defined as the functional decline of tissues and organisms, leading to many human
conditions, such as cancer, neurodegenerative diseases, and hair loss. Although stem cell …

Wound healing is essential to repair the skin after injury. In the epidermis, distinct stem cells
(SCs) populations contribute to wound healing. However, how SCs balance proliferation …

Mammalian epidermis is maintained by stem cells that have the ability to self-renew and
generate daughter cells that differentiate along the lineages of the hair follicles, interfollicular …

How embryonic progenitors coordinate cell fate specification and establish transcriptional
and signaling competence is a fundamental question in developmental biology. Here, we …

Single-cell RNA sequencing (scRNA-seq) of human skin provides a tool for validating
observations from in vitro experimental models. By analyzing a published dataset of healthy …

In recent years, cutaneous epithelial stem cells have attained a genuine celebrity status.
They are considered the key resource for epidermal and skin appendage regeneration, and …

The hair follicle (HF) is a complex miniorgan that serves as an ideal model system to study
stem cell (SC) interactions with the niche during growth and regeneration. Dermal papilla …