Lacidipine: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of hypertension

C Rhoda Lee, HM Bryson - Drugs, 1994 - Springer
Synopsis Lacidipine is an orally administered calcium channel blocker of the
dihydropyridine class, which shows selectivity for vascular smooth muscle over cardiac …

Diltiazem vs. nicardipine on ambulatory and exercise blood pressure and on peripheral hemodynamics.

P Palatini, E Casiglia, GR Graniero… - … journal of clinical …, 1995 - europepmc.org
The present study was aimed at evaluating the antihypertensive efficacy of sustained-
release diltiazem 180 mg vs. sustained-release nicardipine 40 mg both given twice daily. To …

Efficacy of slow-release oral isradipine in moderate-to-severe hypertension with add-on spirapril

RF Abarquez Jr, RG Sy… - American journal of …, 1993 - academic.oup.com
The new slow-release oral formulation (SRO) of isradipine, a dihydropyridine calcium
antagonist, was evaluated in 57 patients who had moderate-tosevere hypertension following …

Second-generation calcium antagonists and ambulatory blood pressure monitoring

JM Mallion, JP Baguet, S Boutelant… - Journal of …, 1995 - journals.lww.com
Ambulatory blood pressure monitoring (ABPM) is a particularly useful method for evaluating
the effects of antihypertensive drugs. ABPM allows the therapeutic effect of an agent to be …

At equipotent doses, isradipine is better tolerated than amlodipine in patients with mild‐to‐moderate hypertension: a double‐blind, randomized, parallel‐group study.

L Hermans, A Deblander, P De Keyser… - British journal of …, 1994 - Wiley Online Library
1. The objective of this double‐blind parallel‐group study was to compare the tolerability of
isradipine and amlodipine, specifically, the side‐effects known to be related to the use of …

A multicenter evaluation of the safety, tolerability, and efficacy of isradipine in the treatment of essential hypertension

CD Sundstedt, PC Rüegg, A Keller, R Waite - The American Journal of …, 1989 - Elsevier
Six hundred outpatients aged between 22 and 84 years with essential hypertension
(diastolic blood pressure of at least 95 mm Hg) entered a multinational, multicenter, single …

A placebo-controlled comparison of diltiazem and amlodipine monotherapy in essential hypertension using 24-h ambulatory monitoring

WW RICHARD, M LINDON - Blood pressure, 1998 - Taylor & Francis
Thirty patients (17 females, median age 55 years) with mild/moderate hypertension (sitting
diastolic blood pressure 95-110 mmHg over 2 consecutive weeks) participated in a study of …

Clinical efficacy and tolerability of isradipine in the treatment of mild-to-moderate hypertension in young and elderly patients

M Batlouni, D Armaganijan, N Ghorayeb… - Journal of …, 1992 - journals.lww.com
The clinical efficacy and tolerability of isradipine was evaluated in 63 patients with mild-to-
moderate hypertension [supine systolic blood pressure (SBP)>= 160 mm Hg and diastolic …

Long-term (2-year) isradipine data in the treatment of mild-to-moderate hypertension

G D'Hont, JP Meurant, DL Clement… - Journal of …, 1992 - journals.lww.com
At the end of a short-term (3-month) study of antihypertensive treatment of mild-to-moderate
hypertension, 141 of the 200 study patients continued into a 2-year follow-up of isradipine as …

Ambulatory blood pressure profiles in patients treated with once-daily diltiazem extended-release or indapamide alone or in combination

LM Prisant… - American Journal of …, 2000 - journals.lww.com
This randomized, double-blind, placebo-controlled, parallel-group study evaluated the
efficacy and safety of single daily dose diltiazem extended-release (XR) and indapamide …