Enteroendocrine cells are specialized secretory lineage cells in the small and large
intestines that secrete hormones and peptides in response to luminal contents. The various …

Enteroendocrine cells (EEC) form the basis of the largest endocrine system in the body.
They secrete multiple regulatory molecules which control physiological and homeostatic …

Highlights•EEC dysfunction occurs in a wide array of GI diseases.•EEC dysfunction is
important in GI symptom generation.•EEC dysfunction affects the maintenance of intestinal …

Enteroendocrine cell differentiation and function in the int... : Current Opinion in
Endocrinology, Diabetes and Obesity Enteroendocrine cell differentiation and function in …

The intestinal epithelium must balance efficient absorption of nutrients with partitioning
commensals and pathogens from the bodies' largest immune system. If this crucial barrier …

The intestinal epithelium represents one of our most important interfaces with the external
environment. It must remain tightly balanced to allow nutrient absorption, but maintain …

Host sensing in the gut microbiota has been crucial in the regulation of intestinal
homeostasis. Although inflammatory bowel diseases (IBDs), multifactorial chronic …

Context: Classical enteroenteroendocrine cell (EEC) biology evolved historically from
identification of scattered hormone-producing endocrine cells within the epithelial mucosa of …

The enteroendocrine system of the gut acts both locally and peripherally, regulating
gastrointestinal function as well as metabolism, energy expenditure, and central appetite …

Gut hormones play a key role in the regulation of food intake, energy expenditure, glucose
homeostasis, lipid metabolism, and a wide range of metabolic functions in response to food …