In HPV–related cancers, the “high-risk” human papillomaviruses (HPVs) are frequently
found integrated into the cellular genome. The integrated subgenomic HPV fragments …

Simple Summary Cells infected with high-risk human papillomaviruses (HPV) can
accumulate DNA damage and eventually transform into HPV-driven cancers. Genome …

Persistent high-risk genus human Alphapapillomavirus (HPV) infections cause nearly every
cervical carcinoma and a subset of tumors in the oropharyngeal tract. During the decades …

High-risk HPV E6 and E7 oncoproteins cooperate to subvert critical host cell cycle
checkpoint control mechanisms in order to promote viral genome replication. This results not …

Infection with high oncogenic risk human papillomavirus types is the etiological factor of
cervical cancer and a major cause of other epithelial malignancies, including vulvar, vaginal …

The development of genomic instability is a hallmark of high-risk human papillomavirus
(HPV) associated cervical carcinogenesis. We have previously shown that the HPV-16 E7 …

Development of invasive cervical cancer upon infection by 'high‐risk'human papillomavirus
(HPV) in humans is a stepwise process in which some of the initially episomal 'high‐risk'type …

Human papillomaviruses (HPV) are the causative agents of cervical cancers. The infectious
HPV life cycle is closely linked to the differentiation state of the host epithelia, with viral …

The human papillomavirus (HPV) genome is integrated into host DNA in most HPV-positive
cancers, but the consequences for chromosomal integrity are unknown. Continuous long …

High-risk human papillomaviruses (HPVs) activate the ataxia telangiectasia mutated-
dependent (ATM) DNA damage response as well as the ataxia telangiectasia mutated …