The L-arginine/NO pathway holds promise as a source of potential therapy target and
biomarker; yet, its status and utility in esophageal squamous cell carcinoma (ESCC) is …

There is a pressing need for molecular targets and biomarkers in gastric cancer (GC). We
aimed at identifying aberrations in L-arginine metabolism with therapeutic and diagnostic …

The L-Arginine/NO pathway is involved in carcinogenesis and immunity. Its diagnostic and
prognostic value in colorectal cancer (CRC) was determined using tandem mass …

Simple Summary Nitric oxide and arginine metabolism in colorectal cancer (CRC) holds
potential for therapeutic intervention. We hypothesized that it can be modulated by oxicams …

Esophageal squamous cell carcinoma (ESCC) is a common malignant tumor with a poor
prognosis due to a lack of early detection. Indeed, the mechanisms underlying ESCC …

Simple Summary Cancers that are 'arginine auxotrophic'rely on extracellular arginine as a
crucial substrate for proliferation and growth. Capitalizing on this vulnerability, there are …

Cancer cells consume a large amount of energy and maintain high levels of anabolism to
promote cell proliferation via metabolic reprogramming. Nuclear factor erythroid 2‐related …

Background Gastric cancer at different locations has distinct prognoses and biological
behaviors, but the specific mechanism is unclear. Methods Non-targeted metabolomics was …

L-Arginine (Arg) is a versatile amino acid that plays crucial roles in a wide range of
physiological and pathological processes. In this study, to investigate the alteration induced …

Colorectal cancer is the leading cause of death from cancer globally. The current treatment
protocol still heavily relies on early detection and surgery. The molecular mechanisms …