Antimicrobial peptides in 2014

G Wang, B Mishra, K Lau, T Lushnikova, R Golla… - Pharmaceuticals, 2015 - mdpi.com
This article highlights new members, novel mechanisms of action, new functions, and
interesting applications of antimicrobial peptides reported in 2014. As of December 2014 …

Novel approaches to combat medical device-associated biofilms

X Li, L Sun, P Zhang, Y Wang - Coatings, 2021 - mdpi.com
Biofilms are aggregates formed as a protective survival state by microorganisms to adapt to
the environment and can be resistant to antimicrobial agents and host immune responses …

Antibiofilm peptides: overcoming biofilm-related treatment failure

M Dostert, MJ Trimble, REW Hancock - RSC advances, 2021 - pubs.rsc.org
Health leaders and scientists worldwide consider antibiotic resistance among the world's
most dangerous pathogens as one of the biggest threats to global health. Antibiotic …

Agents that inhibit bacterial biofilm formation

N Rabin, Y Zheng, C Opoku-Temeng, Y Du… - Future medicinal …, 2015 - Taylor & Francis
In the biofilm form, bacteria are more resistant to various antimicrobial treatments. Bacteria in
a biofilm can also survive harsh conditions and withstand the host's immune system …

Unmet medical needs in antibacterial therapy

LB Rice - Biochemical pharmacology, 2006 - Elsevier
The innate and evolutionary resourcefulness of bacterial pathogens virtually guarantees that
there will always be important areas in which antimicrobial therapy can be improved …

Antimicrobial polymers for anti-biofilm medical devices: state-of-art and perspectives

I Francolini, G Donelli, F Crisante, V Taresco… - … Infections: Volume II, 2014 - Springer
The field of antimicrobial polymers has increasingly grown over the past 10 years, and is
expected to have a further rapid expansion in the next few years. The application of these …

Antibacterial coatings: challenges, perspectives, and opportunities

M Cloutier, D Mantovani, F Rosei - Trends in biotechnology, 2015 - cell.com
Antibacterial coatings are rapidly emerging as a primary component of the global mitigation
strategy of bacterial pathogens. Thanks to recent concurrent advances in materials science …

New frontiers for anti-biofilm drug development

SM Ribeiro, MR Felício, EV Boas, S Gonçalves… - Pharmacology & …, 2016 - Elsevier
Pathogenic microbial biofilm, a consortium of microbial cells protected by a self-produced
polymer matrix, is considered a worldwide challenge due to the inherent antibiotic …

Bacteria responsive antibacterial surfaces for indwelling device infections

C Traba, JF Liang - Journal of controlled release, 2015 - Elsevier
Indwelling device infections now represent life-threatening circumstances as a result of the
biofilms' tolerance to antibiotic treatments. Current antibiotic impregnation approaches …

Design and assessment of anti-biofilm peptides: steps toward clinical application

M Dostert, CR Belanger, REW Hancock - Journal of innate immunity, 2019 - karger.com
Highly antibiotic resistant, microbial communities, referred to as biofilms, cause various life-
threatening infections in humans. At least two-thirds of all clinical infections are biofilm …