Antibiofilm peptides: potential as broad-spectrum agents

D Pletzer, REW Hancock - Journal of bacteriology, 2016 - Am Soc Microbiol
The treatment of bacterial diseases is facing twin threats, with increasing bacterial antibiotic
resistance and relatively few novel compounds or strategies under development or entering …

Surface‐Mediated Release of a Small‐Molecule Modulator of Bacterial Biofilm Formation: A Non‐Bactericidal Approach to Inhibiting Biofilm Formation in …

AH Broderick, AS Breitbach, R Frei… - Advanced …, 2013 - Wiley Online Library
We report an approach to preventing bacterial biofilm formation that is based on the surface‐
mediated release of 5, 6‐dimethyl‐2‐aminobenzimidazole (DMABI), a potent and non …

Antibiofilm peptides: relevant preclinical animal infection models and translational potential

GGOS Silveira, MDT Torres, CFA Ribeiro… - ACS Pharmacology & …, 2021 - ACS Publications
Biofilm-forming bacteria may be 10–1000 times more resistant to antibiotics than planktonic
bacteria and represent about 75% of bacterial infections in humans. Antibiofilm treatments …

Advancing biofilm management through nanoformulation strategies: a review of dosage forms and administration routes

O Simsekli, I Bilinmis, S Celik, G Arık… - Journal of Drug …, 2023 - Taylor & Francis
Biofilms are complex microbial communities formed by the attachment of bacteria or fungi to
surfaces encased in a self-produced polymeric matrix. These biofilms are highly resistant to …

Antibiofilm agents: A new perspective for antimicrobial strategy

XH Li, JH Lee - Journal of Microbiology, 2017 - Springer
Biofilms are complex microbial architectures that attach to surfaces and encase
microorganisms in a matrix composed of self-produced hydrated extracellular polymeric …

Anti-biofilm peptides as a new weapon in antimicrobial warfare

D Pletzer, SR Coleman, REW Hancock - Current opinion in microbiology, 2016 - Elsevier
Highlights•To date no antibiotics have been specifically developed for biofilm infections.•Anti-
biofilm peptides directly address chronic multi-resistant bacterial infections.•They …

Antibiofilm peptides and peptidomimetics with focus on surface immobilization

A Andrea, N Molchanova, H Jenssen - Biomolecules, 2018 - mdpi.com
Bacterial biofilms pose a major threat to public health, as they are associated with at least
two thirds of all infections. They are highly resilient and render conventional antibiotics …

Innovative approaches for controlling clinically relevant biofilms: Current trends and future prospects

K Ivanova, E Ramon, J Hoyo… - Current topics in …, 2017 - ingentaconnect.com
Bacteria that colonize and form biofilms on living tissues and medical devices are a global
healthcare concern. They cause life threatening infections and are associated with …

An overview of biofilm formation–combating strategies and mechanisms of action of antibiofilm agents

ST Asma, K Imre, A Morar, V Herman, U Acaroz… - Life, 2022 - mdpi.com
Biofilm formation on surfaces via microbial colonization causes infections and has become a
major health issue globally. The biofilm lifestyle provides resistance to environmental …

Whether a novel drug delivery system can overcome the problem of biofilms in respiratory diseases?

K Dua, SD Shukla, RK Tekade, PM Hansbro - Drug delivery and …, 2017 - Springer
Biofilm comprises a community of microorganisms which form on medical devices and can
lead to various threatening infections. It is a major concern in various respiratory diseases …