Drug use typically occurs within a social context, and social factors play an important role in
the initiation, maintenance and recovery from addictions. There is now accumulating …

Rationale The endogenous oxytocin system has emerged as an inhibitor of drug-seeking
and stress in preclinical models. Objectives The goal of this study was to examine whether …

Oxytocin has been shown to decrease cocaine taking and seeking in male rats, suggesting
potential treatment efficacy for drug addiction. In the present study, we extended these …

Alcohol (EtOH) is one of the most widely abused recreational drugs and is arguably the most
harmful. However, current treatment options for alcohol‐use disorders generally have limited …

Rationale Oxytocin (OT) is a neuropeptide previously related to reward, learning, memory,
and stress, events associated with cocaine addiction. OT has shown anxiolytic properties in …

Interest for the use of oxytocin as a treatment for addiction began over 40 years ago. Better
known for its roles in parturition, lactation and pair bonding, oxytocin also has anxiolytic …

Drugs that act on the brain oxytocin (OXT) system may provide a much-needed treatment
breakthrough for substance-use disorders. Targeting the brain OXT system has the potential …

It has been previously suggested that oxytocin (Oxt) may act as a natural antipsychotic. To
test this hypothesis, we investigated whether disruption of the oxytocin gene (Oxt−/−) made …

Oxytocin (OT), a neurohypophyseal neuropeptide, affects adaptive processes of the central
nervous system. In the present study, we investigated the effects of OT on extracellular levels …

Accumulating evidence has shown the neuroactive properties of oxytocin (OT), a
neurohypophyseal neuropeptide, and its ability to reduce the abuse potential of drugs. The …