Oxytocin differentially modulates specific dorsal and ventral striatal functional connections with frontal and cerebellar regions

Z Zhao, X Ma, Y Geng, W Zhao, F Zhou, J Wang… - Neuroimage, 2019 - Elsevier
Interactions between oxytocin and the basal ganglia are central in current overarching
conceptualizations of its broad modulatory effects on behavior. Whereas evidence from …

Cocaine abstinence induces emotional impairment and brain region‐specific upregulation of the oxytocin receptor binding

P Georgiou, P Zanos, S Hourani… - European Journal of …, 2016 - Wiley Online Library
The key problem in treating cocaine addiction is the maintenance of a drug‐free state as
negative emotional symptoms during abstinence often trigger relapse. The mechanisms …

Oxytocin reduces alcohol cue-reactivity in alcohol-dependent rats and humans

AC Hansson, A Koopmann, S Uhrig, S Bühler… - …, 2018 - nature.com
Approved pharmacological treatments for alcohol use disorder are limited in their
effectiveness, and new drugs that can easily be translated into the clinic are warranted. One …

Oxytocin directly administered into the nucleus accumbens core or subthalamic nucleus attenuates methamphetamine-induced conditioned place preference

SJ Baracz, PI Rourke, MC Pardey, GE Hunt… - Behavioural brain …, 2012 - Elsevier
Accumulating evidence indicates that the neuropeptide oxytocin (OXY) may modulate
reward-related behavioural responses to methamphetamine (METH) administration. Limited …

The effect of chronic oxytocin treatment during abstinence from methamphetamine self-administration on incubation of craving, reinstatement, and anxiety

NA Everett, SJ Baracz, JL Cornish - Neuropsychopharmacology, 2020 - nature.com
Methamphetamine (METH) abuse is characterised by chronic relapse and anxiety, for which
there are no effective pharmacotherapies. Acute treatment with the neuropeptide oxytocin …

Effects of oxytocin on nicotine withdrawal in rats

KE Manbeck, D Shelley, CE Schmidt… - … Biochemistry and Behavior, 2014 - Elsevier
Abstract Development of medications that attenuate symptoms of nicotine withdrawal may
be useful for facilitating smoking cessation. The neuropeptide oxytocin (OXY) decreases …

Oxytocin and aggression

TR de Jong, ID Neumann - Behavioral pharmacology of neuropeptides …, 2018 - Springer
The neuropeptide oxytocin (OT) has a solid reputation as a facilitator of social interactions
such as parental and pair bonding, trust, and empathy. The many results supporting a pro …

Selective attenuation of cocaine-induced stereotyped behaviour by oxytocin: putative role of basal forebrain target sites

Z Sarnyai, E Babarczy, M Krivan, G Szabo, GL Kovacs… - Neuropeptides, 1991 - Elsevier
The effects of oxytocin (OXT), arginine-and lysine-vasopressin (AVP and LVP) and an OXT-
receptor antagonist on cocaine-induced sniffing behaviour were investigated in rats. OXT …

From ultrasocial to antisocial: a role for oxytocin in the acute reinforcing effects and long‐term adverse consequences of drug use?

IS McGregor, PD Callaghan… - British journal of …, 2008 - Wiley Online Library
Addictive drugs can profoundly affect social behaviour both acutely and in the long‐term.
Effects range from the artificial sociability imbued by various intoxicating agents to the …

Oxytocin modulates behavioural adaptation to repeated treatment with cocaine in rats

Z Sarnyai, É Bíró, E Babarczy, M Vecsernyes, F Laczi… - …, 1992 - Elsevier
Behavioural adaptation to and the effects of the neurohypophyseal peptide, oxytocin, on
repeated treatment with cocaine were investigated in rats. The content of immunoreactive …