Oxytocin differentially modulates specific dorsal and ventral striatal functional connections with frontal and cerebellar regions
Interactions between oxytocin and the basal ganglia are central in current overarching
conceptualizations of its broad modulatory effects on behavior. Whereas evidence from …
conceptualizations of its broad modulatory effects on behavior. Whereas evidence from …
Cocaine abstinence induces emotional impairment and brain region‐specific upregulation of the oxytocin receptor binding
P Georgiou, P Zanos, S Hourani… - European Journal of …, 2016 - Wiley Online Library
The key problem in treating cocaine addiction is the maintenance of a drug‐free state as
negative emotional symptoms during abstinence often trigger relapse. The mechanisms …
negative emotional symptoms during abstinence often trigger relapse. The mechanisms …
Oxytocin reduces alcohol cue-reactivity in alcohol-dependent rats and humans
AC Hansson, A Koopmann, S Uhrig, S Bühler… - …, 2018 - nature.com
Approved pharmacological treatments for alcohol use disorder are limited in their
effectiveness, and new drugs that can easily be translated into the clinic are warranted. One …
effectiveness, and new drugs that can easily be translated into the clinic are warranted. One …
Oxytocin directly administered into the nucleus accumbens core or subthalamic nucleus attenuates methamphetamine-induced conditioned place preference
Accumulating evidence indicates that the neuropeptide oxytocin (OXY) may modulate
reward-related behavioural responses to methamphetamine (METH) administration. Limited …
reward-related behavioural responses to methamphetamine (METH) administration. Limited …
The effect of chronic oxytocin treatment during abstinence from methamphetamine self-administration on incubation of craving, reinstatement, and anxiety
Methamphetamine (METH) abuse is characterised by chronic relapse and anxiety, for which
there are no effective pharmacotherapies. Acute treatment with the neuropeptide oxytocin …
there are no effective pharmacotherapies. Acute treatment with the neuropeptide oxytocin …
Effects of oxytocin on nicotine withdrawal in rats
KE Manbeck, D Shelley, CE Schmidt… - … Biochemistry and Behavior, 2014 - Elsevier
Abstract Development of medications that attenuate symptoms of nicotine withdrawal may
be useful for facilitating smoking cessation. The neuropeptide oxytocin (OXY) decreases …
be useful for facilitating smoking cessation. The neuropeptide oxytocin (OXY) decreases …
Oxytocin and aggression
TR de Jong, ID Neumann - Behavioral pharmacology of neuropeptides …, 2018 - Springer
The neuropeptide oxytocin (OT) has a solid reputation as a facilitator of social interactions
such as parental and pair bonding, trust, and empathy. The many results supporting a pro …
such as parental and pair bonding, trust, and empathy. The many results supporting a pro …
Selective attenuation of cocaine-induced stereotyped behaviour by oxytocin: putative role of basal forebrain target sites
The effects of oxytocin (OXT), arginine-and lysine-vasopressin (AVP and LVP) and an OXT-
receptor antagonist on cocaine-induced sniffing behaviour were investigated in rats. OXT …
receptor antagonist on cocaine-induced sniffing behaviour were investigated in rats. OXT …
From ultrasocial to antisocial: a role for oxytocin in the acute reinforcing effects and long‐term adverse consequences of drug use?
IS McGregor, PD Callaghan… - British journal of …, 2008 - Wiley Online Library
Addictive drugs can profoundly affect social behaviour both acutely and in the long‐term.
Effects range from the artificial sociability imbued by various intoxicating agents to the …
Effects range from the artificial sociability imbued by various intoxicating agents to the …
Oxytocin modulates behavioural adaptation to repeated treatment with cocaine in rats
Z Sarnyai, É Bíró, E Babarczy, M Vecsernyes, F Laczi… - …, 1992 - Elsevier
Behavioural adaptation to and the effects of the neurohypophyseal peptide, oxytocin, on
repeated treatment with cocaine were investigated in rats. The content of immunoreactive …
repeated treatment with cocaine were investigated in rats. The content of immunoreactive …