Previous evidence in an animal model of drug self-administration and drug seeking showed
that acute oxytocin decreased methamphetamine (meth) seeking in male rats, suggesting …

The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

Rationale Initial drug abstinence (modeled here as Extinction Day 1, ED1) is a critical time
point in the progression of addiction that is strongly influenced by stress and sex. ED1 …

The effects of pimozide, a dopamine-receptor blocker and oxytocin, a neurohypophyseal
neuropeptide were investigated in mice on the cocaine-induced exploratory hyperactivity …

Recent data indicate that the neurohypophyseal hormone oxytocin (OXT) and Z-prolyl-d-
leucine (Z-Pro-d-Leu), a synthetic dipeptide derived from the C-terminal part of OXT …

Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) are highly prevalent
and commonly co-occur. The dual diagnosis of PTSD/AUD is associated with serious …

Drug addiction is one of the leading causes of mortality worldwide. Despite great advances
were achieved in understanding the neurobiology of drug addiction, the therapeutic options …

Oxytocin (OXT) has a plethora of effects on brain function. This review provides a historical
overview of the development of research on OXT and drug addiction. By focusing on …

The nucleus accumbens (NAc), also known as the ventral striatum, is a key node of the
mesocorticolimbic reward system. This circuit has received great attention because of its role …

The changes of oxytocin content and mRNA expression in some nuclei were investigated in
morphine-dependent rats using radioimmunoassay (RIA) and in situ hybridization (ISH) …