Background Pediatric papillary thyroid carcinoma (PTC) is clinically and biologically distinct
from adult PTC. We sequenced a cohort of clinically annotated pediatric PTC cases enriched …

Pediatric papillary thyroid carcinoma (PPTC) is clinically distinct from adult-onset disease.
Although there are higher rates of metastasis and recurrence in PPTC, prognosis remains …

Background: Molecular testing (MT) enhances the diagnostic accuracy of thyroid fine-needle
aspiration biopsy, reducing the need for diagnostic lobectomy in adult patients with …

Background: Pediatric papillary thyroid carcinoma (PTC) is a rare malignancy, but with
increasing incidence. Pediatric PTCs have distinct clinical and pathological features and …

BACKGROUND An increase in thyroid cancers, predominantly papillary thyroid carcinoma
(PTC), has been recently reported in children. METHODS The histopathology of 28 …

Pediatric papillary thyroid carcinomas (pPTCs) are often indolent tumors with excellent long-
term outcome, although subsets of cases are clinically troublesome and recur. Although it is …

PURPOSE In 2014, data from a comprehensive multiplatform analysis of 496 adult papillary
thyroid cancer samples reported by The Cancer Genome Atlas project suggested that …

Background We previously described mutation rates of BRAF V600E, RAS, RET-PTC and
PAX8-PPARγ in pediatric subjects with well-differentiated thyroid cancer (WDTC). We …

Context Distant metastases (DM) from childhood differentiated thyroid carcinoma (DTC) are
uncommon and published studies are limited. Objective This work aimed to describe the …

Thyroid cancer is a rare cancer in the pediatric population, but incidences are rising. Thyroid
tumors in children have a unique set of clinical, pathological and molecular features, and …