Oxidant mechanisms in response to ambient air particles

B González-Flecha - Molecular aspects of medicine, 2004 - Elsevier
The toxic effects of air pollution are widely documented. In recent years, however, there has
been an increasing interest in the study of the health effects of particulate matter (PM), a …

Reactive oxygen species in pulmonary inflammation by ambient particulates

F Tao, B Gonzalez-Flecha, L Kobzik - Free Radical Biology and Medicine, 2003 - Elsevier
Exposure to ambient air pollution particles (PM) has been associated with increased
cardiopulmonary morbidity and mortality, particularly in individuals with pre-existing disease …

Pathogenic role of air pollution particulate matter in cardiometabolic disease: evidence from mice and humans

T Marchini, A Zirlik, D Wolf - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: Air pollution is a considerable global threat to human health that dramatically
increases the risk for cardiovascular pathologies, such as atherosclerosis, myocardial …

[HTML][HTML] Mechanistic impact of outdoor air pollution on asthma and allergic diseases

SK Huang, Q Zhang, Z Qiu, KF Chung - Journal of thoracic disease, 2015 - ncbi.nlm.nih.gov
Over the past decades, asthma and allergic diseases, such as allergic rhinitis and eczema,
have become increasingly common, but the reason for this increased prevalence is still …

The physiological effects of air pollution: particulate matter, physiology and disease

JT Pryor, LO Cowley, SE Simonds - Frontiers in Public Health, 2022 - frontiersin.org
Nine out of 10 people breathe air that does not meet World Health Organization pollution
limits. Air pollutants include gasses and particulate matter and collectively are responsible …

Oxidant generation by particulate matter: from biologically effective dose to a promising, novel metric

PJA Borm, F Kelly, N Künzli, RPF Schins… - Occupational and …, 2007 - oem.bmj.com
The classic toxicology paradigm between exposure and response provides the justification
for accurate measurement of exposure to underpin good epidemiological studies aimed at …

Composition of air pollution particles and oxidative stress in cells, tissues, and living systems

AJ Ghio, MS Carraway, MC Madden - Journal of Toxicology and …, 2012 - Taylor & Francis
Epidemiological studies demonstrated an association between increased levels of ambient
air pollution particles and human morbidity and mortality. Production of oxidants, either …

Roles of oxidative stress in signaling and inflammation induced by particulate matter

F Mazzoli-Rocha, S Fernandes… - Cell biology and …, 2010 - Springer
This review reports the role of oxidative stress in impairing the function of lung exposed to
particulate matter (PM). PM constitutes a heterogeneous mixture of various types of particles …

Airborne particulate matter and human health: toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic …

A Valavanidis, K Fiotakis… - Journal of Environmental …, 2008 - Taylor & Francis
Air pollution has been considered a hazard to human health. In the past decades, many
studies highlighted the role of ambient airborne particulate matter (PM) as an important …

Short-term effects of particulate matter: an inflammatory mechanism?

ML Scapellato, M Lotti - Critical reviews in toxicology, 2007 - Taylor & Francis
“Would you tell me please, which way I ought to go from here,” asked Alice.“That depends a
good deal on where you want to go to,” said the cat.(Lewis Carroll, Alice's Adventures in …