Ultrasensitive, multiplexed detection of cancer biomarkers directly in serum by using a quantum dot-based microfluidic protein chip

M Hu, J Yan, Y He, H Lu, L Weng, S Song, C Fan… - ACS …, 2010 - ACS Publications
Sensitive and selective detection for cancer biomarkers are critical in cancer clinical
diagnostics. Here we developed a microfluidic protein chip for an ultrasensitive and …

Micro-/nano-fluidic devices and in vivo fluorescence imaging based on quantum dots for cytologic diagnosis

M Luo, H Yukawa, Y Baba - Lab on a Chip, 2022 - pubs.rsc.org
Semiconductor quantum dots (QDs) possess attractive merits over traditional organic dyes,
such as tunable emission, narrow emission spectra and good resistance against optical …

Nano-bio-chips for high performance multiplexed protein detection: determinations of cancer biomarkers in serum and saliva using quantum dot bioconjugate labels

JV Jokerst, A Raamanathan, N Christodoulides… - Biosensors and …, 2009 - Elsevier
The integration of semiconductor nanoparticle quantum dots (QDs) into a modular,
microfluidic biosensor for the multiplexed quantitation of three important cancer markers …

Quantum dots-based reverse phase protein microarray

M Shingyoji, D Gerion, D Pinkel, JW Gray, F Chen - Talanta, 2005 - Elsevier
CdSe nanocrystals, also called quantum dots (Qdots) are a novel class of fluorophores,
which have a diameter of a few nanometers and possess high quantum yield, tunable …

Microfluidic beads-based immunosensor for sensitive detection of cancer biomarker proteins using multienzyme-nanoparticle amplification and quantum dotslabels

H Zhang, L Liu, X Fu, Z Zhu - Biosensors and Bioelectronics, 2013 - Elsevier
This study reports the development of a microfluidic beads-based immunosensor for
sensitive detection of cancer biomarker α-fetoprotein (AFP) that uses multienzyme …

Simultaneous quantitative detection of multiple tumor markers with a rapid and sensitive multicolor quantum dots based immunochromatographic test strip

C Wang, F Hou, Y Ma - Biosensors and Bioelectronics, 2015 - Elsevier
A novel multicolor quantum dots (QDs) based immunochromatographic test strip (ICTS) was
developed for simultaneous quantitative detection of multiple tumor markers, by utilizing …

On-chip dual detection of cancer biomarkers directly in serum based on self-assembled magnetic bead patterns and quantum dots

X Yu, HS Xia, ZD Sun, Y Lin, K Wang, J Yu… - Biosensors and …, 2013 - Elsevier
A sandwich immunoassay method for rapid detection of dual cancer biomarkers in serum on
a magnetic field controllable microfluidic chip (MFCM-Chip) was established. A nickel …

Multicolor quantum dot-encoded microspheres for the detection of biomolecules

Q Ma, X Wang, Y Li, Y Shi, X Su - Talanta, 2007 - Elsevier
The biocompatible semiconductor quantum dots (QDs) have unique photophysical
properties, which provide important advantages over organic dyes and lanthanide probes in …

Quantum dot-based immunochromatography test strip for rapid, quantitative and sensitive detection of alpha fetoprotein

Q Yang, X Gong, T Song, J Yang, S Zhu, Y Li… - Biosensors and …, 2011 - Elsevier
Rapid, quantitative detection of tumor markers with high sensitivity and specificity is critical to
clinical diagnosis and treatment of cancer. We describe here a novel portable fluorescent …

Antibody quantum dot conjugates developed via copper-free click chemistry for rapid analysis of biological samples using a microfluidic microsphere array system

N Kotagiri, Z Li, X Xu, S Mondal, A Nehorai… - Bioconjugate …, 2014 - ACS Publications
Antibody-based proteomics is an enabling technology that has significant implications for
cancer biomarker discovery, diagnostic screening, prognostic and pharmacodynamic …