The relationship between the placental serotonin pathway and fetal growth restriction
S Ranzil, DW Walker, AJ Borg, EM Wallace… - Biochimie, 2019 - Elsevier
Fetal growth restriction (FGR) is a complex disorder of human pregnancy that leads to poor
health outcomes in offspring. These range from immediate risks such as perinatal morbidity …
health outcomes in offspring. These range from immediate risks such as perinatal morbidity …
Serotonin system in the human placenta–the knowns and unknowns
M Perić, I Bečeheli, L Čičin-Šain, G Desoye… - Frontiers in …, 2022 - frontiersin.org
The biogenic monoamine serotonin (5-hydroxytryptamine, 5-HT) is a chemical messenger
widely distributed in the brain and various other organs. Its homeostasis is maintained by the …
widely distributed in the brain and various other organs. Its homeostasis is maintained by the …
Postnatal changes in serotonin1 receptors following prenatal alterations in serotonin levels: further evidence for functional fetal serotonin1 receptors
PM Whitaker-Azmitia, JM Lauder, A Shemmer… - Developmental Brain …, 1987 - Elsevier
Recent work by ourselves and others has indicated that serotonin (5-HT) acts as a regulator
of neuronal growth in fetal tissue, probably through an action on the high affinity 5-HT …
of neuronal growth in fetal tissue, probably through an action on the high affinity 5-HT …
Placental source for 5-HT that tunes fetal brain development.
The article focuses on the potential importance of extra-embryonically derived tryptophan or
5-HT in modulating fetal developmental processes. It notes that disruption of 5-HT, which …
5-HT in modulating fetal developmental processes. It notes that disruption of 5-HT, which …
The developmental disruptions of serotonin signaling may involved in autism during early brain development
CJ Yang, HP Tan, YJ Du - Neuroscience, 2014 - Elsevier
Autism is a developmental disorder defined by the presence of a triad of communication,
social and stereo typical behavioral characteristics with onset before 3 years of age. In spite …
social and stereo typical behavioral characteristics with onset before 3 years of age. In spite …
Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6
O Riccio, G Potter, C Walzer, P Vallet, G Szabó… - Molecular …, 2009 - nature.com
The discovery that a common polymorphism (5-HTTLPR, short variant) in the human
serotonin transporter gene (SLC6A4) can influence personality traits and increase the risk …
serotonin transporter gene (SLC6A4) can influence personality traits and increase the risk …
Serotonin receptor expression in human prefrontal cortex: balancing excitation and inhibition across postnatal development
Serotonin and its receptors (HTRs) play critical roles in brain development and in the
regulation of cognition, mood, and anxiety. HTRs are highly expressed in human prefrontal …
regulation of cognition, mood, and anxiety. HTRs are highly expressed in human prefrontal …
Roles for serotonin in neurodevelopment: more than just neural transmission
During pre-and early postnatal development, the neurotransmitter serotonin (5-HT)
modulates cell proliferation, migration and programmed cell death, as well as cell shape and …
modulates cell proliferation, migration and programmed cell death, as well as cell shape and …
Maternal serotonin is crucial for murine embryonic development
F Côté, C Fligny, E Bayard… - Proceedings of the …, 2007 - National Acad Sciences
The early appearance of serotonin and its receptors during prenatal development, together
with the many effects serotonin exerts during CNS morphogenesis, strongly suggest that …
with the many effects serotonin exerts during CNS morphogenesis, strongly suggest that …
The effect of antenatal depression and selective serotonin reuptake inhibitor treatment on nerve growth factor signaling in human placenta
H Kaihola, J Olivier, IS Poromaa, H Åkerud - PLoS One, 2015 - journals.plos.org
Depressive symptoms during pregnancy are common and may have impact on the
developing child. Selective serotonin reuptake inhibitors (SSRIs) are the most prescribed …
developing child. Selective serotonin reuptake inhibitors (SSRIs) are the most prescribed …