The relationship between the placental serotonin pathway and fetal growth restriction

S Ranzil, DW Walker, AJ Borg, EM Wallace… - Biochimie, 2019 - Elsevier
Fetal growth restriction (FGR) is a complex disorder of human pregnancy that leads to poor
health outcomes in offspring. These range from immediate risks such as perinatal morbidity …

Serotonin system in the human placenta–the knowns and unknowns

M Perić, I Bečeheli, L Čičin-Šain, G Desoye… - Frontiers in …, 2022 - frontiersin.org
The biogenic monoamine serotonin (5-hydroxytryptamine, 5-HT) is a chemical messenger
widely distributed in the brain and various other organs. Its homeostasis is maintained by the …

Postnatal changes in serotonin1 receptors following prenatal alterations in serotonin levels: further evidence for functional fetal serotonin1 receptors

PM Whitaker-Azmitia, JM Lauder, A Shemmer… - Developmental Brain …, 1987 - Elsevier
Recent work by ourselves and others has indicated that serotonin (5-HT) acts as a regulator
of neuronal growth in fetal tissue, probably through an action on the high affinity 5-HT …

Placental source for 5-HT that tunes fetal brain development.

A Bonnin, P Levitt - Neuropsychopharmacology, 2012 - search.ebscohost.com
The article focuses on the potential importance of extra-embryonically derived tryptophan or
5-HT in modulating fetal developmental processes. It notes that disruption of 5-HT, which …

The developmental disruptions of serotonin signaling may involved in autism during early brain development

CJ Yang, HP Tan, YJ Du - Neuroscience, 2014 - Elsevier
Autism is a developmental disorder defined by the presence of a triad of communication,
social and stereo typical behavioral characteristics with onset before 3 years of age. In spite …

Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6

O Riccio, G Potter, C Walzer, P Vallet, G Szabó… - Molecular …, 2009 - nature.com
The discovery that a common polymorphism (5-HTTLPR, short variant) in the human
serotonin transporter gene (SLC6A4) can influence personality traits and increase the risk …

Serotonin receptor expression in human prefrontal cortex: balancing excitation and inhibition across postnatal development

EK Lambe, SG Fillman, MJ Webster… - PLoS …, 2011 - journals.plos.org
Serotonin and its receptors (HTRs) play critical roles in brain development and in the
regulation of cognition, mood, and anxiety. HTRs are highly expressed in human prefrontal …

Roles for serotonin in neurodevelopment: more than just neural transmission

G Di Pino, R Moessner, KP Lesch… - Current …, 2004 - ingentaconnect.com
During pre-and early postnatal development, the neurotransmitter serotonin (5-HT)
modulates cell proliferation, migration and programmed cell death, as well as cell shape and …

Maternal serotonin is crucial for murine embryonic development

F Côté, C Fligny, E Bayard… - Proceedings of the …, 2007 - National Acad Sciences
The early appearance of serotonin and its receptors during prenatal development, together
with the many effects serotonin exerts during CNS morphogenesis, strongly suggest that …

The effect of antenatal depression and selective serotonin reuptake inhibitor treatment on nerve growth factor signaling in human placenta

H Kaihola, J Olivier, IS Poromaa, H Åkerud - PLoS One, 2015 - journals.plos.org
Depressive symptoms during pregnancy are common and may have impact on the
developing child. Selective serotonin reuptake inhibitors (SSRIs) are the most prescribed …