Growth modulation of fibroblasts by chitosan-polyvinyl pyrrolidone hydrogel: implications for wound management?

M Risbud, A Hardikar, R Bhonde - Journal of biosciences, 2000 - Springer
Wounds in adults and fetuses differ in their healing ability with respect to scar formation. In
adults, wounds lacking the epidermis exhibit excess collagen production and scar formation …

Comparative study of collagen and gelatin in chitosan-based hydrogels for effective wound dressing: Physical properties and fibroblastic cell behavior

S Mousavi, AB Khoshfetrat, N Khatami… - Biochemical and …, 2019 - Elsevier
The influence of collagen as an effective substitute for gelatin was investigated on properties
of chitosan/gelatin hydrogels for fibroblasts growth and attachment for wound dressing …

Assessment of reinforced poly (ethylene glycol) chitosan hydrogels as dressings in a mouse skin wound defect model

SH Chen, CT Tsao, CH Chang, YT Lai, MF Wu… - Materials Science and …, 2013 - Elsevier
Wound dressings of chitosan are biocompatible, biodegradable, antibacterial and
hemostatic biomaterials. However, applications for chitosan are limited due to its poor …

Development of a new chitosan hydrogel for wound dressing

MP Ribeiro, A Espiga, D Silva… - Wound repair and …, 2009 - Wiley Online Library
Wound healing is a complex process involving an integrated response by many different cell
types and growth factors in order to achieve rapid restoration of skin architecture and …

Controlled release of protein from gelatin/chitosan hydrogel containing platelet-rich fibrin encapsulated in chitosan nanoparticles for accelerated wound healing in an …

F Mirjalili, M Mahmoodi - International Journal of Biological Macromolecules, 2023 - Elsevier
The physiological healing process is disrupted in many cases using the current wound
healing procedures, resulting in delayed wound healing. Hydrogel wound dressings provide …

Chitosan based hydrogels and their applications for drug delivery in wound dressings: A review

H Hamedi, S Moradi, SM Hudson, AE Tonelli - Carbohydrate polymers, 2018 - Elsevier
Advanced development of chitosan hydrogels has led to new drug delivery systems that can
release their active ingredients in response to environmental stimuli. This review considers …

Biocompatibility and gelation of chitosan–glycerol phosphate hydrogels

R Ahmadi, JD de Bruijn - Journal of Biomedical Materials …, 2008 - Wiley Online Library
The aim of this study was to evaluate the cytotoxicity and gelation of thermosensitive
chitosan‐β‐glycerol phosphate (GP) solutions, which undergo sol–gel transition around …

Application of a PDGF-containing novel gel for cutaneous wound healing

R Judith, M Nithya, C Rose, AB Mandal - Life sciences, 2010 - Elsevier
AIM: The objective of this study was to develop an acellular provisional matrix to mimic the
extracellular matrix (ECM) of a wound site, and to evaluate its potential for in vivo dermal …

Production of chitosan PVA PCL hydrogels to bind heparin and induce angiogenesis

M Yar, G Gigliobianco, L Shahzadi, L Dew… - … Journal of Polymeric …, 2016 - Taylor & Francis
New blood vessel formation is an essential part of wound healing to provide cells with the
nutrients and oxygen for their survival. Many nonhealing ulcers fail to heal because of poor …

Analysis of the effects of chitosan on inflammation, angiogenesis, fibroplasia, and collagen deposition in polyvinyl alcohol sponge implants in rat wounds

RF Diegelmann, JD Dunn… - Wound Repair and …, 1996 - Wiley Online Library
Chitosan is a large molecular weight, positively charged polysaccharide extracted and
purified from the chitin of crab shells. This compound has been shown to have hemostatic …