Improving prediction of disease outcome for inflammatory bowel disease: progress through systems medicine

F Giachero, A Jenke, M Zilbauer - Expert Review of Clinical …, 2021 - Taylor & Francis
ABSTRACT Introduction: Inflammatory bowel diseases (IBDs) are lifelong conditions
causing relapsing inflammation of the intestine. In the absence of a cure, clinical …

[HTML][HTML] Biomarkers in inflammatory bowel diseases: insight into diagnosis, prognosis and treatment

M Norouzinia, V Chaleshi, AHM Alizadeh… - … and Hepatology from …, 2017 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic disease of unknown etiology which mostly
involves the intestine and requires a personalized approach for treatment. IBD represents a …

Prognostication in inflammatory bowel disease

EA Spencer, M Agrawal, T Jess - Frontiers in Medicine, 2022 - frontiersin.org
Personalized care in inflammatory bowel diseases (IBD) hinges on parsing the
heterogeneity of IBD patients through prognostication of their disease course and …

Predictors: How to Approach the Individualization of Treatment

D Ceballos - Inflammatory Bowel Diseases, 2021 - academic.oup.com
The “big data” in inflammatory bowel disease opens a route of detection of predictors that
can determine the prognosis of each patient and allow the individualized selection of more …

Disease prognostic biomarkers in inflammatory bowel Diseases—A reality check

M Zilbauer, R Heuschkel - Journal of Crohn's and Colitis, 2022 - academic.oup.com
Inflammatory bowel diseases [IBD] such as Crohn's disease [CD] and ulcerative colitis [UC]
are complex conditions presenting with a wide range of phenotypes. Given major variation …

Predictors and early markers of response to biological therapies in inflammatory bowel diseases

G Privitera, D Pugliese, GL Rapaccini… - Journal of clinical …, 2021 - mdpi.com
Inflammatory bowel diseases (IBD) are chronic conditions that primarily affect the
gastrointestinal tract, with a complex pathogenesis; they are characterized by a significant …

Pathogenesis and precision medicine for predicting response in inflammatory bowel disease: advances and future directions

RD Little, T Jayawardana, S Koentgen… - …, 2024 - egastroenterology.bmj.com
The pathogenesis of inflammatory bowel disease (IBD) is complex and multifactorial.
Undertreated disease has substantial individual and societal consequences. Current patient …

Biomarkers for personalizing IBD therapy: The quest continues

R Atreya, MF Neurath - Clinical Gastroenterology and Hepatology, 2024 - Elsevier
Despite recent advances in the understanding of the pathogenesis of inflammatory bowel
diseases (IBD) and advent of multiple targeted therapies, approximately one-third of patients …

Molecular profiling of inflammatory bowel disease: is it ready for use in clinical decision-making?

HS Lee, I Cleynen - Cells, 2019 - mdpi.com
Inflammatory bowel disease (IBD) is a heterogeneous disorder in terms of age at onset,
clinical phenotypes, severity, disease course, and response to therapy. This underlines the …

[HTML][HTML] Advancing the precision management of inflammatory bowel disease in the era of omics approaches and new technology

XY Liu, H Tang, QY Zhou, YL Zeng… - World Journal of …, 2023 - ncbi.nlm.nih.gov
There is great heterogeneity among inflammatory bowel disease (IBD) patients in terms of
pathogenesis, clinical manifestation, response to treatment, and prognosis, which requires …