[HTML][HTML] Role of T cell—glial cell interactions in creating and amplifying central nervous system inflammation and multiple sclerosis disease symptoms

ES Huseby, D Kamimura, Y Arima… - Frontiers in cellular …, 2015 - frontiersin.org
Multiple Sclerosis (MS) is an inflammatory disease of the Central Nervous System (CNS)
that causes the demyelination of nerve cells and destroys oligodendrocytes, neurons and …

[HTML][HTML] Astrocytes and inflammatory T helper cells: a dangerous liaison in multiple sclerosis

M Kunkl, C Amormino, V Tedeschi, MT Fiorillo… - Frontiers in …, 2022 - frontiersin.org
Multiple Sclerosis (MS) is a neurodegenerative autoimmune disorder of the central nervous
system (CNS) characterized by the recruitment of self-reactive T lymphocytes, mainly …

Control of autoimmune CNS inflammation by astrocytes

V Rothhammer, FJ Quintana - Seminars in immunopathology, 2015 - Springer
Multiple sclerosis is a neurologic disease caused by immune cell infiltration into the central
nervous system, resulting in gray and white matter inflammation, progressive demyelination …

T cell–neuron interaction in inflammatory and progressive multiple sclerosis biology

T Brummer, F Zipp, S Bittner - Current Opinion in Neurobiology, 2022 - Elsevier
Multiple sclerosis (MS) is a chronic autoimmune condition of the central nervous system
(CNS) characterized by acute inflammatory relapses, chronic neuro-axonal degeneration …

When encephalitogenic T cells collaborate with microglia in multiple sclerosis

Y Dong, VW Yong - Nature Reviews Neurology, 2019 - nature.com
Immune cells mediate critical inflammatory and neurodegenerative processes in the CNS in
individuals with multiple sclerosis (MS). In MS, activated microglia, border-associated …

Relapsing–remitting central nervous system autoimmunity mediated by GFAP-specific CD8 T cells

K Sasaki, A Bean, S Shah, E Schutten… - The Journal of …, 2014 - journals.aai.org
Multiple sclerosis (MS) is an inflammatory disease of the CNS that causes the demyelination
of nerve cells and destroys oligodendrocytes, neurons, and axons. Historically, MS has been …

[HTML][HTML] Regulation of neuroinflammatory properties of glial cells by T cell effector molecules

CK Prajeeth, J Huehn, M Stangel - Neural Regeneration …, 2018 - journals.lww.com
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disorder that is
thought to be mediated by autoreactive T lymphocytes that find their way into the central …

Glia connect inflammation and neurodegeneration in multiple sclerosis

Y Sun, H Yu, Y Guan - Neuroscience Bulletin, 2023 - Springer
Multiple sclerosis (MS) is regarded as a chronic inflammatory disease that leads to
demyelination and eventually to neurodegeneration. Activation of innate immune cells and …

Astrocytes in multiple sclerosis: a product of their environment

A Nair, TJ Frederick, SD Miller - Cellular and molecular life sciences, 2008 - Springer
It has long been thought that astrocytes, like other glial cells, simply provide a support
mechanism for neuronal function in the healthy and inflamed central nervous system (CNS) …

The ins and outs of central nervous system inflammation—lessons learned from multiple sclerosis

V Ramaglia, O Rojas, I Naouar… - Annual review of …, 2021 - annualreviews.org
Multiple sclerosis (MS) is a chronic disease that is characterized by the inappropriate
invasion of lymphocytes and monocytes into the central nervous system (CNS), where they …