Obesity: a disease or a biological adaptation? An update

JP Chaput, E Doucet, A Tremblay - Obesity reviews, 2012 - Wiley Online Library
Obesity is characterized by the accumulation of excess body fat and can be conceptualized
as the physical manifestation of chronic energy excess. An important challenge of today's …

The interplay between adipose tissue and vasculature: Role of oxidative stress in obesity

Y Zhou, H Li, N Xia - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Cardiovascular diseases (CVDs) rank the leading cause of morbidity and mortality globally.
Obesity and its related metabolic syndrome are well-established risk factors for CVDs …

Oxygenation of adipose tissue: A human perspective

IG Lempesis, RLJ van Meijel… - Acta …, 2020 - Wiley Online Library
Obesity is a complex disorder of excessive adiposity, and is associated with adverse health
effects such as cardiometabolic complications, which are to a large extent attributable to …

[HTML][HTML] Adipose tissue and insulin resistance in obese

B Ahmed, R Sultana, MW Greene - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Currently, obesity has become a global health issue and is referred to as an epidemic.
Dysfunctional obese adipose tissue plays a pivotal role in the development of insulin …

Oxidative stress-induced risk factors associated with the metabolic syndrome: a unifying hypothesis

I Grattagliano, VO Palmieri, P Portincasa… - The Journal of nutritional …, 2008 - Elsevier
Although the biochemical steps linking insulin resistance with the metabolic syndrome have
not been completely clarified, mounting experimental and clinical evidence indicate …

Hypoxia, oxidative stress and fat

N Netzer, H Gatterer, M Faulhaber, M Burtscher… - Biomolecules, 2015 - mdpi.com
Metabolic disturbances in white adipose tissue in obese individuals contribute to the
pathogenesis of insulin resistance and the development of type 2 diabetes mellitus …

Biochemical and immunological changes in obesity

B Barakat, MEF Almeida - Archives of Biochemistry and Biophysics, 2021 - Elsevier
Obesity is a syndemia that promotes high expenditures for public health, and is defined by
the excess of adipose tissue that is classified according to its function and anatomical …

Obesity: epidemiology, pathophysiology, and therapeutics

X Lin, H Li - Frontiers in endocrinology, 2021 - frontiersin.org
Obesity is a complex multifactorial disease that accumulated excess body fat leads to
negative effects on health. Obesity continues to accelerate resulting in an unprecedented …

Oxidative stress associated to dysfunctional adipose tissue: a potential link between obesity, type 2 diabetes mellitus and breast cancer

AB Crujeiras, A Díaz-Lagares, MC Carreira… - Free radical …, 2013 - Taylor & Francis
Diabetes mellitus and breast cancer are two important health problems. Type 2 diabetes
(T2DM) and obesity are closely linked with both being associated with breast cancer …

Association between obesity, inflammation and insulin resistance: Insights into signaling pathways and therapeutic interventions

SS Garg, K Kushwaha, R Dubey, J Gupta - Diabetes research and clinical …, 2023 - Elsevier
Obesity, a metabolic disorder, is becoming a worldwide epidemic that predominantly
increases the risk for various diseases including metabolic inflammation, insulin resistance …