Spontaneous remission of adult acute myeloid leukemia with t(8;16)(p11;p13)/MOZ-CBP fusion

T Hoshino, T Taki, S Takada, N Hatsumi… - Leukemia & …, 2018 - Taylor & Francis
The translocation t (8; 16)(p11; p13), which results in fusion of the MOZ/MYST3/KAT6A gene
(8p11) and CBP/CREBBP gene (16p13), is characterized by unique morphologic and …

Two novel variants of MOZ-CBP fusion transcripts in spontaneously remitted infant leukemia with t (1; 16; 8)(p13; p13; p11), a new variant of t (8; 16)(p11; p13)

K Terui, T Sato, S Sasaki, K Kudo, T Kamio… - Haematologica, 2008 - haematologica.org
Translocation t (8; 16)(p11; p13) involving the MOZ/MYST3 gene (8p11) and the
CBP/CREBBP gene (16p13) is associated with the FAB M4/M5 subtype of acute myeloid …

Type I MOZ/CBP (MYST3/CREBBP) is the most common chimeric transcript in acute myeloid leukemia with t(8;16)(p11;p13) translocation

M Rozman, M Camós, D Colomer… - Genes …, 2004 - Wiley Online Library
Abstract The t (8; 16)(p11; p13) fuses the MOZ (MYST3) gene at 8p11 with CBP (CREBBP)
at 16p13 and is associated with an infrequent but well‐defined type of acute myeloid …

[PDF][PDF] A novel specific signature of pediatric MOZ-CBP acute myeloid leukemia

S Serravalle, F Melchionda, A Astolfi, V Libri… - Leukemia …, 2010 - sfera.unife.it
The reciprocal chromosomal rearrangement t (8; 16)(p11; p13) is rare both in adult and
pediatric acute myeloid leukemias (AML) accounting 0.2–0.4% of de novo AML and 6.5% of …

RT‐PCR analysis of the MOZ‐CBP and CBP‐MOZ chimeric transcripts in acute myeloid leukemias with t(8;16)(p11;p13)

I Panagopoulos, M Isaksson, C Lindvall… - Genes …, 2000 - Wiley Online Library
Abstract The translocation t (8; 16)(p11; p13) is associated with a subtype of acute monocytic
leukemia (AML M5) characterized morphologically by erythrophagocytosis and clinically by …

RT-PCR and FISH analysis of acute myeloid leukemia with t (8; 16)(p11; p13) and chimeric MOZ and CBP transcripts: breakpoint cluster region and clinical …

HH Schmidt, S Strehl, D Thaler, D Strunk, H Sill… - Leukemia, 2004 - nature.com
Abstract The translocation t (8; 16)(p11; p13) is associated with acute myeloid leukemia
displaying monocytic differentiation (AML FAB M4/5) and fuses the MOZ (also named …

Deep spontaneous molecular remission in a patient with congenital acute myeloid leukemia expressing a novel MOZ-p300 fusion transcript

Y Ikawa, R Nishimura, H Maeba, T Fujiki… - Leukemia & …, 2018 - Taylor & Francis
Adult acute myeloid leukemia (AML) with t (8; 16)(p11; p13) is a rare subgroup with a poor
prognosis. However, Coenen et al.[1] reported that spontaneous remission occurred in 7 of …

Detection of MOZ-CBP fusion in acute myeloid leukemia with 8; 16 translocation

JA Crowley, Y Wang, AP Rapoport, Y Ning - Leukemia, 2005 - nature.com
Chromosome translocations that result in gene fusion and expression of the fusion gene
products are frequently observed in acute myeloid leukemia (AML). The recurrent …

Genomic characterization of MOZ/CBP and CBP/MOZ chimeras in acute myeloid leukemia suggests the involvement of a damage‐repair mechanism in the origin of …

I Panagopoulos, M Isaksson, C Lindvall… - Genes …, 2003 - Wiley Online Library
Abstract The t (8; 16)(p11; p13), which is strongly associated with acute myeloid leukemia
(AML) displaying monocytic differentiation, erythrophagocytosis by the leukemic cells, and a …

The clinical utility of genetic testing for t (8; 16)(p11; p13) in congenital acute myeloid leukemia

T Daifu, I Kato, K Kozuki, K Umeda… - Journal of Pediatric …, 2014 - journals.lww.com
Acute myeloid leukemia (AML) with t (8; 16)(p11; p13) is known to have very poor prognosis
in adults. In contrast, the prognosis is not clear in pediatric patients and chemotherapy is …