Radiation is frequently administered for cancer treatment, but resistance or remission
remains common. Cancer cells alter their metabolism after radiotherapy to reduce its …

High-grade gliomas, glioblastomas (GB), are refractory to conventional treatment combining
surgery, chemotherapy, mainly temozolomide, and radiotherapy. This highlights an urgent …

Metformin and cancer therapy : Current Opinion in Oncology Metformin and cancer therapy :
Current Opinion in Oncology Log in or Register Subscribe to journalSubscribe Get new issue …

Radiotherapy and chemotherapy are widespread clinical modalities for cancer treatment.
Among other biological influences, hypoxia is a main factor limiting the efficacy of …

Simple Summary This literature analysis is focused on the pleiotropic action associated with
metformin treatment. Precisely, metformin treatment exerts many health effects, mainly by …

Metformin is a well-known anti-diabetic drug that has been repurposed for several emerging
applications, including as an anti-cancer agent. It boasts the distinct advantages of an …

Metformin is a widely used drug in today's prescriptions by physicians due to its specific
effects in treating and curing type II diabetes. Diabetes is a common disease that may occur …

Metformin inhibits cancer cell proliferation, and epidemiology studies suggest an association
with increased survival in patients with cancer taking metformin; however, the mechanism by …

Purpose: Hypoxia is associated with resistance to radiotherapy and chemotherapy and
activates transcription factors that support cell survival and migration. We measured the …

Tumor hypoxia is recognized as a limiting factor for the efficacy of radiotherapy, because it
enhances tumor radioresistance. It is strongly suggested that assessing tumor oxygenation …