Connexins: sensors and regulators of cell cycling

M Vinken, E Decrock, E De Vuyst, R Ponsaerts… - … et Biophysica Acta (BBA …, 2011 - Elsevier
It is nowadays well established that gap junctions are critical gatekeepers of cell
proliferation, by controlling the intercellular exchange of essential growth regulators. In …

Connexins and pannexins: Important players in tumorigenesis, metastasis and potential therapeutics

SV Graham, JX Jiang, M Mesnil - International journal of molecular …, 2018 - mdpi.com
Since their characterization more than five decades ago, gap junctions and their structural
proteins—the connexins—have been associated with cancer cell growth. During that period …

Connexins and their channels in cell growth and cell death

M Vinken, T Vanhaecke, P Papeleu, S Snykers… - Cellular signalling, 2006 - Elsevier
Direct communication between cells, mediated by gap junctions, is nowadays considered as
an indispensable mechanism in the maintenance of cellular homeostasis. In fact, gap …

[HTML][HTML] Non-channel functions of connexins in cell growth and cell death

M Vinken, E Decrock, L Leybaert, G Bultynck… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Cellular communication mediated by gap junction channels and hemichannels, both
composed of connexin proteins, constitutes two acknowledged regulatory platforms in the …

Introduction: connexins, pannexins and their channels as gatekeepers of organ physiology

M Vinken - Cellular and Molecular Life Sciences, 2015 - Springer
Homeostasis relies on the intimate interplay between extracellular, intracellular and
intercellular signaling networks. Direct communication between adjacent cells is mediated …

Connexins: a myriad of functions extending beyond assembly of gap junction channels

HA Dbouk, RM Mroue, ME El-Sabban… - Cell Communication and …, 2009 - Springer
Connexins constitute a large family of trans-membrane proteins that allow intercellular
communication and the transfer of ions and small signaling molecules between cells …

[HTML][HTML] Gap junction and hemichannel-independent actions of connexins on cell and tissue functions–an update

JZ Zhou, JX Jiang - FEBS letters, 2014 - Elsevier
Connexins, a family of transmembrane proteins, are components of both gap junction
channels and hemichannels, which mediate the exchange of ions and small molecules …

Biological role of connexin intercellular channels and hemichannels

R Kar, N Batra, MA Riquelme, JX Jiang - Archives of biochemistry and …, 2012 - Elsevier
Gap junctions (GJ) and hemichannels (HC) formed from the protein subunits called
connexins are transmembrane conduits for the exchange of small molecules and ions …

Non-canonical roles of connexins

R Van Campenhout, A Cooreman, K Leroy… - Progress in biophysics …, 2020 - Elsevier
Graphical abstract Gap junctions mediate cellular communication and homeostasis by
controlling the intercellular exchange of small and hydrophilic molecules and ions. Gap …

Connexin and pannexin channels in cancer

JX Jiang, S Penuela - BMC cell biology, 2016 - Springer
Communication among cells via direct cell-cell contact by connexin gap junctions, or
between cell and extracellular environment via pannexin channels or connexin …