1, 2, 4-Oxadiazole-based bio-isosteres of benzamides: Synthesis, biological activity and toxicity to zebrafish embryo

S Yang, CL Ren, TY Ma, WQ Zou, L Dai… - International Journal of …, 2021 - mdpi.com
To discover new compounds with broad spectrum and high activity, we designed a series of
novel benzamides containing 1, 2, 4-oxadiazole moiety by bioisosterism, and 28 …

Structure-based Bioisosterism design, synthesis, biological activity and toxicity of 1, 2, 4-oxadiazole substituted benzamides analogues containing pyrazole rings

MT Tu, YY Shao, S Yang, BL Sun, YY Wang, CX Tan… - Molecules, 2022 - mdpi.com
In order to discover pesticidal lead compounds with high activity and low toxicity, a series of
novel benzamides substituted with pyrazole-linked 1, 2, 4-oxadiazole were designed via …

Benzamides substituted with quinoline-linked 1, 2, 4-oxadiazole: Synthesis, biological activity and toxicity to zebrafish embryo

BL Sun, YY Wang, S Yang, MT Tu, YY Shao, Y Hua… - Molecules, 2022 - mdpi.com
To develop new compounds with high activity, broad spectrum and low-toxicity, 17
benzamides substituted with quinoline-linked 1, 2, 4-oxadiazole were designed using the …

Synthesis, biological activity and toxicity to zebrafish of benzamides substituted with pyrazole-linked 1, 2, 4-oxadiazole

Y Shao, M Tu, S Yang, Y Wang, B Sun, J Shi, C Tan… - RSC …, 2022 - pubs.rsc.org
To find pesticidal lead compounds with high activity, a series of novel benzamides
substituted with pyrazole-linked 1, 2, 4-oxadiazole was designed and synthesized by using …

Novel Pyridyl–Oxazole Carboxamides: Toxicity Assay Determination in Fungi and Zebrafish Embryos

S Chen, DL Zhang, CL Ren, WQ Zou, XY Tian, XH Du… - Molecules, 2021 - mdpi.com
Eight novel pyridyl–oxazole carboxamides were evaluated against fungi and displayed
good fungicidal activities against Botrytis cinereal and Rhizoctonia solani. Preliminary …

Synthesis, antifungal activities and molecular docking studies of benzoxazole and benzothiazole derivatives

B Luo, D Li, AL Zhang, JM Gao - Molecules, 2018 - mdpi.com
Based on benzoxazole and benzothiazole scaffold as an important pharmacophore, two
series of 2-(aryloxymethyl) benzoxazole and benzothiazole derivatives were synthesized …

Synthesis, Biological Activity, and Toxicity to Zebrafish Embryo of Benzamides Substituted with 1, 2, 4-Oxadiazole-Linked Pyrazole

Y Wang, C Wu, Z Li, J Wu, Y Chen, M Li… - … Agricultural Science & …, 2023 - ACS Publications
To explore novel pesticidal lead compounds with potential activity, a series of new
benzamide compounds substituted with 1, 2, 4-oxadiazole-linked pyrazole were designed …

Design and synthesis of novel triazole antifungal derivatives by structure-based bioisosterism

C Sheng, X Che, W Wang, S Wang, Y Cao… - European journal of …, 2011 - Elsevier
The incidence of life-threatening fungal infections is increasing dramatically. In an attempt to
develop novel antifungal agents, our previously synthesized phenoxyalkylpiperazine …

Antifungal Activity, Structure‐Activity Relationship and Molecular Docking Studies of 1, 2, 4‐Triazole Schiff Base Derivatives

Y Dong, M Li, Y Hao, Y Feng, Y Ren… - Chemistry & …, 2023 - Wiley Online Library
Fourteen novel Schiff base compounds (AS‐1∼ AS‐14) containing 5‐amino‐1H‐1, 2, 4‐
triazole‐3‐carboxylic acid and substituted benzaldehyde were successfully synthesized …

Synthesis and antimicrobial activity of new heteroaryl (aryl) thiazole derivatives molecular docking studies

V Kartsev, A Geronikaki, A Zubenko, A Petrou… - Antibiotics, 2022 - mdpi.com
Herein, we report the design, synthesis, and evaluation of the antimicrobial activity of new
heteroaryl (aryl) thiazole derivatives. The design was based on a molecular hybridization …