Colorectal cancer (CRC) places a considerable burden on individuals and society in
Europe, being the second most common cause of cancer-related death in the region. While …

In the last 15 years, significant progress in the management of colorectal cancer (CRC) has
been achieved with several new agents licensed extending median overall survival for stage …

Background: Systematic evaluation and validation of new prognostic and predictive markers,
technologies and interventions for colorectal cancer (CRC) is crucial for optimizing patients' …

Simple Summary Colorectal cancer is one of the leading causes of cancer-associated
deaths worldwide. From the 1960s to 2002, the standard systemic treatment consisted of …

Simple Summary Metastatic colorectal cancer (mCRC) represents a significant burden in
cancer-related morbidity and mortality. The study of mCRC-related genetic alterations and …

Background Colorectal cancer (CRC) is the third most common malignant neoplasm
worldwide and the fourth leading cause of cancer-related deaths. This article reviews the …

Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. Several
important scientific discoveries in the molecular biology of CRC have changed clinical …

According to the Global Cancer Statistics 2020, colorectal cancer (CRC) represents the third
most frequent malignancy worldwide, and is the second in terms of mortality [1]. Its higher …

Colon cancer (CC) therapies have improved patient outcomes significantly over the last
decades in both the adjuvant and metastatic settings. With the introduction of a number of …

A severe global health concern is the rising incidence and mortality rate of colorectal cancer
(CRC). Chemotherapy, which is typically used to treat CRC, is known to have limited …