Emerging role of interleukin‐33 in autoimmune diseases

C Pei, M Barbour, KJ Fairlie‐Clarke, D Allan… - …, 2014 - Wiley Online Library
Summary Interleukin‐33 (IL‐33) is a member of the IL‐1 cytokine family. It predominantly
induces type 2 immune responses and thus is protective against atherosclerosis and …

IL-6, IL-17 and STAT3: a holy trinity in auto-immunity?

A Camporeale, V Poli - Frontiers in bioscience, 2012 - iris.unito.it
Interleukin-6 (IL-6) is a pleiotropic cytokine involved in the regulation of the cross talk
between haematopoietic/immune cells and stromal cells, including the onset and resolution …

[PDF][PDF] Interleukin 10 (IL-10) regulatory cytokine and its clinical consequences

E Bijjiga, AT Martino - J Clin Cell Immunol S, 2013 - researchgate.net
IL-10 involvement in disease progression continues to be evaluated. Through these studies
it has become evident that the role of IL-10 in immunological conditions encompasses a …

The paradoxical role of IL-10 in immunity and cancer

MH Mannino, Z Zhu, H Xiao, Q Bai, MR Wakefield… - Cancer letters, 2015 - Elsevier
Abstract Interleukin-10 (IL-10) produced by a wide-variety of cells is a highly pleiotropic
cytokine. It has been implicated in the pathogenesis and/or development of autoimmune …

Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease

W Ouyang - Cytokine & growth factor reviews, 2010 - Elsevier
IL-22, an IL-10 family cytokine, is produced by different leukocyte subsets, including T cells,
NK cells and lymphoid tissue inducer (LTi) cells. IL-22 mediates the crosstalk between …

Role of IL‐22 in homeostasis and diseases of the skin

DV Lopez, M Kongsbak‐Wismann - Apmis, 2022 - Wiley Online Library
Interleukin‐22 (IL‐22) is a cytokine mainly produced by T cells and innate lymphoid cells
(ILC). IL‐22 primarily targets non‐hematopoietic cells such as epithelial cells and fibroblasts …

Regulation of inflammatory responses by IL-17F

XO Yang, SH Chang, H Park, R Nurieva… - The Journal of …, 2008 - rupress.org
Although interleukin (IL) 17 has been extensively characterized, the function of IL-17F, which
has an expression pattern regulated similarly to IL-17, is poorly understood. We show that …

IL-17 in chronic inflammation: from discovery to targeting

A Beringer, M Noack, P Miossec - Trends in molecular medicine, 2016 - cell.com
Interleukin-17 (IL-17) is a cytokine which elicits protection against extracellular bacterial and
fungal infections and which plays important roles in inflammation. However, when produced …

Biology and therapeutic potential of interleukin-10

M Saraiva, P Vieira, A O'garra - Journal of Experimental Medicine, 2019 - rupress.org
The cytokine IL-10 is a key anti-inflammatory mediator ensuring protection of a host from
over-exuberant responses to pathogens and microbiota, while playing important roles in …

The IL-17 family cytokines in immunity and disease

R Pappu, V Ramirez-Carrozzi, N Ota… - Journal of clinical …, 2010 - Springer
Introduction Accumulating evidence suggests that the interleukin (IL)-17 cytokines are major
players in the immune response to foreign pathogens. In addition, the pathogeneses of a …